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 Skin cancer prevention strategies
 Moisturizer use linked to increased skin cancer
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dan

603 Posts

Posted - 08/16/2008 :  02:05:17  Show Profile  Reply with Quote
Irradiation of mice with UVB twice a week for 20 weeks resulted in mice with a high risk of developing skin tumors over the next several months in the absence of further irradiation with UVB. Topical applications of commercially available moisturizing creams once a day, 5 days a week for 17 weeks to these high-risk mice increased significantly the rate of formation of tumors and the rate of increase in tumor size per mouse.

The studies indicated that treatment of high-risk mice with Dermabase, Dermovan, Eucerin, or Vanicream for 17 weeks increased the total number of tumors by 69% , 95% , 24% , and 58%, respectively.

The results indicate that several commercially available moisturizing creams increase the rate of formation and number of tumors when applied topically to UVB-pretreated high-risk mice. Further studies are needed to determine the effects of topical applications of moisturizing creams on sunlight-induced skin cancer in humans.

http://www.nature.com/jid/journal/vaop/ncurrent/abs/jid2008241a.html

RidgebackDogs

USA
103 Posts

Posted - 08/16/2008 :  10:06:58  Show Profile  Reply with Quote
Verrry interesting! Wonder what 100mg equates to on how much a person would use on their face or body? (Dirk Pearson & Sandy Shaw in their original Life Extension book said that the amount of BHT force-fed to mice that were already tumor-prone represented an amount that no person would ever be consume even if it was in everything they ate and its equivalent would be over a pound per day.) I wonder what size of lotion a 100 mg would be - unfortunately I do not have equipment to measure this (drat!) - anybody out there have an idea how much cream this would be? It was applied 1x/day to mice. It will be interesting to have another look-see on the ingredients in these creams. Most of these I have already looked at the indgredients and have not bought them because of objectionable ingredients.
Right now I am using Jason Baby cream w/beta glucan but i am nervous about rancid oils in some of the natural products as I know from experience with rancid vit e capsules that worsened stretch marks.
Before I had the skin cancers on my face I was using Mary Kay formula system I for dry skin 2x/day - masking 1x/week - using sunscreen every am - then had problem with break-out from sunscreens, finally went to using aveeno on face as i was using that for body lotion. I remember the mask used to irritate my nose so I quit using that 1st - but a run through of their ingredients shows many objectionable chemicals. I think you need an advanced degree in chemistry to buy moisturizers - i won't even touch make-up any more! Petrochemical derived dyes are not going on my skin anymore - i cant afford it!!!! It's ridiculous! i don't what is "safe" to use anymore or what isn't?
Thanks for the info Dan - every little bit helps!
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RidgebackDogs

USA
103 Posts

Posted - 08/25/2008 :  23:03:55  Show Profile  Reply with Quote
Had another look at this citation on PubMed - what is interesting is they used a special blend cream (as a control i suppose) on the mice and this cream did not cause tumors in the uvb exposed, high-risk mice - sure would like to know what is in that cream!
Dan do you know how this information can be gotten?
Thank you!
EWG Skin Deep only had ingredients on Eucerin and it wasn't clear which one - but most of those ingredients are in a lot of moisturizers.
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dan

603 Posts

Posted - 08/31/2008 :  22:00:05  Show Profile  Reply with Quote
The Custom Blend cream that did not promote skin cancer is patented to Rutgers university and pharmaceutical company Johnson and Johnson. The publication reports its ingredients as; purified water, propylene glycol, stearyl alcohol, cetyl alcohol, polysorbate 20, isopropyl myristate, C12-15 alkyl benzoate, benzoic acid, glycerin, and sodium hydroxide.

http://news.scotsman.com/nhshealth/Moisturised-mice.4397991.jp

The Conney team asked Johnson & Johnson to make them a "custom blend" moisturizer without two ingredients previously linked to skin irritation (sodium lauryl sulfate) and tumor promotion (mineral oil).

http://www.webmd.com/melanoma-skin-cancer/news/20080814/moisturizers-up-skin-cancer-in-mice?page=2

Vanicreme ingredients from http://www.coolibar.com/05301.html : purified water, white petrolatum, cetearyl alcohol and ceteareth-20, sorbitol solution, propylene glycol, simethicone, glyceryl monostearate, polyethylene glycol monostearate, sorbic acid, BHT

Ironically, the Vanicreme product on the website above boasts a seal of approval by the Skin Cancer Foundation!

Dermabase ingredients: water, petrolatum, mineral oil, cetostearyl alcohol, propylene glycol, sodium laurel sulfate, isopropyl palmitate, imidazolidinyl urea, methylparaben and propylparaben.

Eucerin ingredients: Triple purified water, petrolatum, mineral oil, ceresin, lanolin alcohol, methylchloroisothiazolinone, and methylisothiazolinone (Good thing they purified the water!)

Dermovan, a wholesale-only product used as a base to which other ingredients are added by compounding pharmacists, was made by Healthpoint Ltd. until the product was discontinued in 2006. ingredients: water, glyceryl stearate and stearamidoethyl diethylamine, glycerin, mineral oil, cetyl esters, cetyl alcohol, butylparaben, methylparaben, and propylparaben.
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thanks01

USA
170 Posts

Posted - 09/02/2008 :  17:10:28  Show Profile  Reply with Quote
Suggestion:
There are a number of people on this board working on problems with their LIPS. What Dan is showing here about moisturizers probably applies also to various commercial LIP BALMS. Try reading the ingredients for any you are using and compare to Dan's list above. Maybe we are better off suffering from dry lips than putting on lip-balm.
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dan

603 Posts

Posted - 09/02/2008 :  20:42:59  Show Profile  Reply with Quote
Thanks thanks01!

Here is a list of ingredients for Chapstick Classic Original:

Drug Facts
Active ingredients Purposes
Padimate O 1.5%....... ....................................................................Sunscreen
White petrolatum 44% .............................................................Skin protectant

Inactive ingredients
arachidyl propionate, camphor, carnauba wax, cetyl alcohol, D&C red no. 6 barium lake, FD&C yellow no. 5 aluminum lake, fragrance, isopropyl lanolate, isopropyl myristate, lanolin, light mineral oil, methylparaben, octyldodecanol, oleyl alcohol, paraffin, phenyl trimethicone, propylparaben, titanium dioxide, white wax
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RidgebackDogs

USA
103 Posts

Posted - 09/02/2008 :  21:39:28  Show Profile  Reply with Quote
Dan! Thank you! Thank you! Thank you! How do you find this info?
It helps to know what to avoid.
I must say that the areas post-Mohs that are irritated on my nose also correspond to areas that I was putting vaseline on after the surgery as that is what they recommend to use on the incision site. I wonder what could be used besides that. I will have to look into this. Also the Mary Kay products are mineral oil based. A lot of lipsticks contain mineral oil. Lip balms often have either mineral oil or petrolatum. I am going to be avoiding products that contain these ingredients. Burts Bees and Badger lip balms do not contain mineral oil or petrolatum.
Chapstick 100% Natural Lip Butter ingredients:
Ingredients Helianthus Annuus (Sunflower) Seed Oil, Jojoba Esters, Euphorbia Cerifera (Candelilla) Wax, Cocos Nucifera (Coconut) Oil, Flavor, Beeswax, Copernicia Cerifera (Carnauba) Wax, Butyrospermum Parkii (Shea Butter), Glycine Soja (Soybean) Lipids, Mangifera Indica (Mango) Seed (Mango Butter), Octyldodecanol, Olea Europaea (Olive) Fruit Oil (Olive Butter), Persea Gratissima (Avocado) Oil (Avocado Butter), Rubus Idaeus (Raspberry) Seed Oil (Raspberry Butter), Tocopherol, Tocopheryl Acetate

As far as moisturizers go I have not found one that I am completely happy with - still searching. Any suggestions are more than welcome. Thank you!


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Misty

USA
1 Posts

Posted - 09/24/2008 :  17:41:24  Show Profile  Reply with Quote
What about coconut oil for a moisturizer? I have been trying to go with all-natural things instead of factory-made concoctions in an attempt to simplify everything.
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dan

603 Posts

Posted - 09/25/2008 :  01:14:22  Show Profile  Reply with Quote
I like the idea of using coconut oil in place of moisturizers. In addition to killing certain strains of candida yeast that can take hold in the skin, it can also act somewhat in place of a sunscreen.

I found this excerpt from the book Coconut Cures: Preventing and Treating Common Health Problems with Coconut
By Bruce Fife

"Sunburns damage the skin and promote cancer so you want to avoid excessive exposure. Unfortunately, it is not easy to tell when you have had enough until it is too late. Sunscreen isn't the answer. Sunscreens with a protection factor of as little as 8 block about 94 percent of the UV rays and thus prevent vitamin D synthesis. Some studies show that the chemicals in these creams may promote cancer, so they could do more harm than good.

A far better option to sunscreen would be to use coconut oil. Applied on the skin it protects against sunburn as well as cancer. Unlike sunscreen, coconut oil does not block the UV rays that are necessary for vitamin D synthesis. It protects the skin and underlying tissues from damage excessive exposure can cause. Instead of burning or turning red it produces a light tan, depending on the length of time you spend in the sun. Consuming coconut oil also strengthens the skin and makes it more resilient and less prone to sunburn.

The types of fats we eat affect how our bodies respond to sunlight. Fats in the diet are incorporated into skin tissues. Polyunsaturated fats are easily oxidized by sunlight, causing destructive free-radical reactions that initiate the cancer process. People who eat a lot of polyunsaturated oils are more vulnerable to sunburn and skin cancer.

Assimilation and utilization of vitamin D is also affected by dietary fat intake. Both polyunsaturated and monounsaturated fats in the diet decrease the binding of vitamin D to D-binding proteins and thus make the vitamin less available for utilization in the body.' Unsaturated fats like soybean and canola oils actually promote vitamin D deficiency. Saturated fats, such as coconut oil, do not have this effect. So if you are going to get the most benefit from sunbathing, coconut oil should be the main source of fat in your diet."

The question remains about using refined or unrefined coconut oil. I am sure everyone will say unrefined is better but it does have a coconut smell that can get annoying.
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anivoc

636 Posts

Posted - 09/28/2008 :  09:21:14  Show Profile  Reply with Quote
Wow!

Frightening...

Taking a step back and thinking about this, aside from allowing important vitamin D from the sun to be formed in our bodies naturally, are the sunscreens that we are placing on our skin actually inducing tumor growth of already damaged skin while protecting us from future UV damage?

To add to the good question Thaks01 brought up about the correlation to chapstick type products and skin cancer on lips..
Are women who use lipstick more likely to get skin cancer on their lips than men? Though I am sure there are men that get this, I don't remember any men posting here about skin cancer on their lips.


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RidgebackDogs

USA
103 Posts

Posted - 11/18/2008 :  21:55:44  Show Profile  Reply with Quote
quote:
Originally posted by anivoc

Wow!

Frightening...






Ya!
i stay away from all make-up and sun screen - i used to use more sun screen than make-up - also went to using less saturated fats and more polys and monos - so now i enjoy butter as well as coconut oil - it is the best for popcorn any-who-how!
Wonder when they will be coming out with this "moisturizer" that doesn't cause skin cancers???
right now i am using coconut oil - extra virgin unrefined made by Garden of Life. I have been using it for about a month 1-2x/day on some spots - i am not sure if they are all improving but they don't look worse (i do notice i start to get red dots on my face - they say that happens w/aldara when it gets the immune response going)- it does clear up a rash i sometimes get by my lips within a day or two. also in Oct i had a nasty bump that appeared like overnight on my cheekbone that was bleeding and it cleared that up within 4 days being applied 2-3x/day. i am thinking of mixing the coconut oil w/neem oil next for a few spots on my face.
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jpwonders

6 Posts

Posted - 03/11/2013 :  23:53:21  Show Profile  Reply with Quote
I use BWC [beauty w/ out cruelty] When I can afford it. At night coconut oil if not too tired to put it on {alway the case} so it never gets on. I hate now $$ tight so back to the crappy daytime lotion. Coconut oil in the daytime is too oily and don't want to lessen the life of my clothing that I have worn my whole life and want to keep. BWC has no mineral oil or parabins and is at least cheaper than other natural lotions. Jason is good but costs more so I went w/ BWC for the last year. My skin cancer has gotten much worse, but not from lotions, but from smart meters and wifi, but I dread when the bottle of BWC runs out and have to do cheap lotion. Doesn't do the joob as well.
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freespirit

1 Posts

Posted - 03/15/2013 :  19:26:42  Show Profile  Reply with Quote
Can you tell me more about smart meters and cancer or direct me to some information. My city is in the process of installing these things now. Thank you.
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Disclaimer: The three most common types of skin cancer are basal cell carcinoma, squamous cell carcinoma, and melanoma. While melanoma is the most dangerous type, keep in mind that any cancer and potentially some cancer treatments can cause injury or death. The various views expressed in these public forums should not be considered as medical advice. See your qualified health-care professional for medical attention, advice, diagnosis, and treatments.