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 Skin cancer treatments
 PDQ, Curaderm, and/or Sunspot?
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Corihere

6 Posts

Posted - 09/08/2007 :  12:39:30  Show Profile  Reply with Quote
So many creams! So many testimonials! I'm wishing to quickly understand what, if any, combination of these creams I should have on hand to treat my precancers on my face. I've received my Sunspot, and just started with that. Now see there are posts that recommend mixing with Curaderm or other combinations.

Are Curaderm and PDQ more aggressive, and therefore should be mixed with the Sunspot for a treatment approach?

I'd appreciate the help and feedback!

Thanks so much,
Corihere

rocco

77 Posts

Posted - 09/08/2007 :  14:12:08  Show Profile  Reply with Quote
I'd say many of us would recommend NOT using the PDQ, especially on your face. I might use PDQ on a hand, arm or even upper chest, but never again on my face. It hurts a bit, and scars, and may not remedy the problem without multiple uses.

I have had pretty decent results on AK's on the face using SunSpot ES. It takes a while to get rid of them sometimes, maybe a month or more. But SunSPot is a very good product. I have never used Curaderm so I can't help you there.

As far as combinations, SunSpot and orange oil seems a good pairing. I think it is forrest that mixes orange oil with a little DMSO. Seems like that would work well too.
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dan

611 Posts

Posted - 09/08/2007 :  15:04:49  Show Profile  Reply with Quote
Some other factors to consider:

PDQ: about $90 US, 40 doses claimed enough to treat 20 lesions, but does not mention the word cancer
Ingredients unknown

Curaderm: about $120 US, a usual treatment regime will last 7 to 60 days at 2-10 times per day.
Ingredients disclosed: Solasodine Glycosides (BEC), salicylic acid (aspirin), and urea.
Curaderm backing scientific research, see http://www.curaderm.net/publications/publications.aspx

SunSpot ES: about $24 US (Vitacost), no claims for skin cancer, apply twice daily
Ingredients: Water, aloe vera, propylene, glycol, salicylic acid, urea, carbomer 940, tea tree oil, menthol, gylcoalkaloid extract, imidazolidinyl urea.
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anivoc

668 Posts

Posted - 09/08/2007 :  15:24:29  Show Profile  Reply with Quote
Just my opinion on this.

Curaderm is at least 4 times the price of sunspot es with the same active ingredient bec5 from eggplant.

I have used curaderm and sunspot and when using sunspot as directed with curaderm ( keep covered and don't let the area dry out) and adding a cream to keep it moist, to me, works just as well if not better.

I have not used PDQ but have used bloodroot paste. After looking at PDQ testimonials and pictures and speaking to the manufacturer ( they were very illusive of their "magic potion" ingredients )I believe PDQ is like a diluted and filtered version of bloodroot paste.

Since you have the sunspot try it. It can't hurt and will at least keep what you have at bay.

If I were to recommend anything at this point in time based on recent results on this BBS, I would say do the eggplant / vinegar paste treatment...or the 35% hydrogen peroxide treatment. Both have had some significantly good results by people on this board.

Whatever you do, if you can, keep both a written and photographic journal for proof of the pudding if you are successful.


Tom
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dan

611 Posts

Posted - 09/08/2007 :  16:12:53  Show Profile  Reply with Quote
I agree the vinegar and eggplant remedy is perhaps the best. If you think this is a wimpy remedy, Curaderm used to claim that their product was safe because one eggplant had 30 times the BEC as one tube of Curaderm. So don't skip over that $3600 eggplant. Glycoalkaloids are commercially extracted with acetic acid (vinegar). The commercial products have advantages in terms of uniformity, research, the other synergistic ingredients they include, and smell, but not the active ingredient.

I think the vinegar eggplant home remedy can be simplified to chopping an eggplant, putting it into a bottle, filling it with vinegar, covering, and letting it sit for several days, shaking occasionally. I would then apply the vinegar brine liberally and follow with aloe vera gel. Find an aloe vera brand without alcohol but with urea, such as Trader Joes. The aloe takes away much of the vinegar smell. Adding a crushed aspirin tablet may also be helpful.
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fforest

103 Posts

Posted - 09/08/2007 :  17:55:57  Show Profile  Reply with Quote
Glycoalkaloids are commercially extracted with acetic acid (vinegar)

Dan where did you find this infomation?...I looked all over the internet for how the Glycoalkaloids are commercially extracted from eggplant but came up empty handed...I would like to read about this if you have a link...
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Corihere

6 Posts

Posted - 09/08/2007 :  18:20:56  Show Profile  Reply with Quote
Thank you everyone! I'll be trying the sunspot, and the look into the Eggplant and vinegar solution!
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dan

611 Posts

Posted - 09/09/2007 :  00:04:48  Show Profile  Reply with Quote
fforest, I probably should have said "can be commercially extracted " instead of "are commercially extracted." I did searches on "glycoalkaloids extraction" and "glycoalkaloids acetic" and other combinations and found lots of hits, although the majority dealt with potato glycoalkaloids. Eggplant is in the same plant family as potatoes and tomatoes. I found a 2007 academic dissertation of "Glycoalkaloid Content and Starch Structure in Solanum Species and Interspecific Somatic Potato Hybrids" by Tiina Väänänen of the University of Helsinki that says:

"Glycoalkaloids are soluble in acidic aqueous solutions and polar organic solvents, including
acetonitrile, methanol, ethanol, and propanol. In most cases glycoalkaloid extraction from
plant materials is carried out with dilute acetic acid (1-5%), a nontoxic and inexpensive
solvent. Organic solvents such as methanol (Fitzpatrick and Osman, 1974) and methanol
mixed with chloroform (Wang et al., 1972) have been selected especially for fresh samples. It
has been reported, however, that aqueous solvents are more efficient for dried materials than
non-aqueous (Bushway et al., 1986; Friedman and McDonald, 1995). Combinations of
different solvents have been prepared to achieve effective extraction of amphiphilic
glycoalkaloids, and they have been thoroughly reviewed (Friedman and McDonald, 1997,
1999). The possible hydrolysis of glycoalkaloids is avoided by using dilute weak acids or
organic solvents at room temperature. However, aqueous methanol containing 1%
hydrochloric acid has also been used (Kozukue et al., 1999; Stobiecki et al., 2003). Bisulfite is
sometimes added to prevent oxidation of the extract (Hellenäs, 1986; Edwards and Cobb,
1996). Different procedures are used if glycoalkaloids are hydrolyzed in the sample
preparation step. For example, two-phase hydrolysis and concomitant hydrolysis-extraction
procedures have been succesfully applied to glycoalkaloid mixtures (van Gelder, 1984;
Laurila et al., 1996; Weissenberg, 2001).

After extraction, the glycoalkaloids are either precipitated with ammonia (Fitzpatrick and
Osman, 1974; Bushway et al., 1979; Dao and Friedman, 1996; Sotelo and Serrano, 2001;
Kozukue and Friedman, 2003), or isolated with solid-phase extraction (SPE) (Carman et al.,
1986; Bushway et al., 1986; Jonker et al., 1992; Friedman et al., 1994; Abell and Sporns,
1996; Edwards and Cobb, 1996; Friedman et al., 1998a; Esposito et al., 2002), or a
combination of these methods. After precipitation with ammonia at pH 10, the dried
glycoalkaloid precipitation is dissolved in methanol or some other suitable solvent, or further
extracted with butanol (Sotelo and Serrano, 2000)."

It is interesting that the potency of glycoalkaloids does not appear to be affected by ammonia, one of the components of the vinegar eggplant orange oil ammonia remedy. The dissertation has enough references to remedy many sleepless nights. The link is only available in google cache, so it may disappear soon.
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fforest

103 Posts

Posted - 09/09/2007 :  10:29:51  Show Profile  Reply with Quote
Glycoalkaloids are soluble in acidic aqueous solutions and polar organic solvents, including
acetonitrile, methanol, ethanol, and propanol. In most cases glycoalkaloid extraction from
plant materials is carried out with dilute acetic acid (1-5%), a nontoxic and inexpensive

Well there you go...The above says acetic acid (vinegar) works for extacting glycoalkaloids...Good job finding this...I am strangely very interested in organic chemistry and find my self falling asleep at the same time..lol..

The skin absorbs the eggplant vinegar mix in a nice way but the creams focuse better on one spot in my opinion...



Edited by - fforest on 09/09/2007 10:30:33
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Disclaimer: The three most common types of skin cancer are basal cell carcinoma, squamous cell carcinoma, and melanoma. While melanoma is the most dangerous type, keep in mind that any cancer and potentially some cancer treatments can cause injury or death. The various views expressed in these public forums should not be considered as medical advice. See your qualified health-care professional for medical attention, advice, diagnosis, and treatments.