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agare
17 Posts |
 Posted - 02/05/2018 : 17:46:30
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| Dear BobCA. My doctor took a sample of tissue and sent it off for analysis, that is, a biopsy. The reason I used a melaleuca cream was firstly, simply to cover the petty spurge sap, and possibly, aid in penetration because I knew from the failure with my nodular skin cancer, that if the sap can't penetrate it won't work. However, there has also been research on the use of melaleuca combined with DMSO for skin cancer carried out at the University of Western Australia which showed positive results, so this could certainly do no harm. As I remember, they used 90% DMSO, so if this gets the oil into the bloodstream, they were happy to do that. The research was discontinued because funding dried up. I have also read that using DMSO with the extract of devil's apple or aubergine improved its effect, although it is not encouraged by the main researcher on it, Dr Bill Cham, although I think he has experimented with it. |
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BobCA
43 Posts |
Posted - 02/05/2018 : 18:47:58
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| Thanks for all that great personal info. I am not sure what you mean by “nodular” skin cancer. I’ve not seen any research papers on SCC nor BCC that use that term. Melanoma on the other hand can create a tumor like nodule that can go very deep. We don’t want to be messing around with that one. If you could, please provide a link to the research performed with Ingenol mebutate enhancers like melaleuca or DMSO. I’d love to read up on that. DMSO was pioneered by Russian athletes back in the late 70s/early 80s to accelerate soft tissue damage. The premise was that DMSO could travel through the skin into joints or tendons and actually stimulate the would healing response, IE it is an irritant. Some users added aspirin to DMSO to get localized effects. Still not sure why we need DMSO to get IM beneath the skin. After all we are treating skin cancers. With all that said I really appreciate you taking the time to share your personal experiences. Please shoot me any research that you’ve come across that is not in the mainstream journals. My basis for application and use has come from published articles. Thanks man, keep fighting the good fight. |
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agare
17 Posts |
Posted - 02/05/2018 : 19:18:26
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| Dear BobCA, I haven't read anything on using DMSO with petty spurge except on this website. I did find something some time ago on its use with the extract from Devil's Apple, but I am not sure where. Combining it with tea tree oil was my idea after reading an article on tea-tree oil here: http://www.news.uwa.edu.au/201006292609/events/tea-tree-oil-offers-hope-skin-cancer-patients and then corresponding with the researchers for details. Here is something on nodular BCC. When my doctor saw that I had this, he immediately recommended surgery where he was happy to try petty spurge with the non-nodular form. I have not had a recurrence of the nodular form, but would like to be prepared for it, which is the reason I am interested in what could supplement petty spurge. It is weird that there is no further research on melaleuca oil given the successes reported, and going in to this I have come to realize how treatments of anything which work but don't generate big profits are not likely to get supported by mainstream medicine and are sometimes disparaged (for instance, fish oil for arthritis). The problem with alternative medicine is that its practicioners appear unable to sort out the good from the useless or bad alterntives. Google is a help in sorting this out, but it takes time. |
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agare
17 Posts |
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BobCA
43 Posts |
Posted - 02/05/2018 : 19:30:59
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Awesome!!!! Great article. Did you see all the different types of BCC??
Superficial Basal Cell Carcinoma of Skin
Nodular Basal Cell Carcinoma of Skin
Infiltrating Basal Cell Carcinoma of Skin
Micronodular Basal Cell Carcinoma of Skin
Fibroepithelial Basal Cell Carcinoma of Skin
Basal Cell Carcinoma of Skin with Adnexal Differentiation
Basosquamous Carcinoma
Keratotic Basal Cell Carcinoma of Skin
Anyway, topical treatment like 5,5 Flourocil and Imiquimode were recommended and if they work then IB (sold as Picato) might work even better. Different chemical action but doesn’t involve weeks of treatment.
Thanks so much for this,
Bob |
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KMWS
18 Posts |
Posted - 02/05/2018 : 19:34:19
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| Agare did you use Ingenol mebutate (Petty Spurge) on your nodular BCC or did you have surgery to get rid of it? |
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agare
17 Posts |
Posted - 02/05/2018 : 22:15:15
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| I tried petty spurge, using two lots of treatment, each treatment being three successive applications on each day, using a good amount of sap. Each time the scab came off, the nodule was still there, although slightly smaller. I tried to measure this accurately. I was told that being on my upper lip, just under my nose, it was not a good place to be because it could spread down and get into my skull, so I had surgery. I was prepared for surgery and then sent home the first time because the site was inflamed due to my treatment with petty spurge. I was told that there was about a 12% chance of recurrence after surgery, and this has not occurred, and I think it lightly that the change of recurrence after surgery was reduced by my petty spurge treatment. |
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BobCA
43 Posts |
Posted - 02/05/2018 : 22:44:28
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Here is s really good article on all types of BCCs. You’ll notice that they mention 5,5 Flororoucil and Imiquimode. The first is a cyctotoxic agent and the second is an immune system modifier. I have used both.
Ingenol mebutate is both cyctoxic and an immune modifier. Same clinical result when applied once per day for 3 days. Leave on for 6 hours before washing. No sweating and AVOID eyes.
https://www.dermnetnz.org/topics/basal-cell-carcinoma |
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BobCA
43 Posts |
Posted - 03/29/2018 : 10:00:15
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Hi All, I wanted to relay an active and ongoing story. About 3 months ago I noticed a spot on my upper chest about 8mm (1/2"). It was reddish and I suspected it was either AK or BCC so I hit it with Petty Spurge, once a day for 3 days. It reacted quite strongly, PS continues to work even after the 3 day application. I use petrolatum to keep the scab from forming and after a week or so it had cleared up nicely. Well, that same spot has returned and now it feels like it may be a little deeper. It doesn't appear to be just on teh surface. I once again hit it with PS and it cleared most of it but not all of it and since I could still feel it beneath the skin I decided to let my derm take a look. He said it looked liked BCC to him but we took a shave biopsy just to be sure. I will know in 10 days and will let you all know. If it BCC we will excise it.
On another note: I have had this scaly spot on my nose forever. Not red just scaly, tried burning it off with Ni, tried 5,5,fluororocil, and of course PS. It always comes back. Punch biopsy showed advanced AK but no BCC or SCC. I am now going to try Imiquimode as the chemical reaction is different from PS. My derm says to keep hitting with different methods to keep it at bay. He doesn't want it to go deeper and develop into BCC. |
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BobCA
43 Posts |
Posted - 03/31/2018 : 20:38:38
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| Follow up on the biopsy, came back positive for BCC as I anticipated. So far PS has been 100% accurate in identifying AK and BCC. Every lesion that reacted with PS that I have had biopsied has been positive for AK or BCC. When it’s AK I just keep an eye on it and keep hitting every 4 months or so with PS but when it’s BCC I don’t mess around and have it excised. This particular lesion reacted strongly to PS so I waited 3 weeks and hit it again. This time the reaction was much less. 2 weeks after this I had the biopsy. This tells me that while PS can be effective for AKs and surface BCCs, it does not go deep enough to get all of a subsurface BCC. Probably why the FFA has it cleared as a treatment for AKs only. There are so many types of BCCs that I would guard against believing PS can completely resolve all of them. Work with your derm to stay on top of any lesions and treatment methods. |
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waverider
76 Posts |
Posted - 04/07/2018 : 22:30:48
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| What a bumper crop of petty spurge here in So. California this year! I guess it is the late arrival of some semblance of cool winter + heavy rains a couple of weeks ago. In the past, I was used to seeing a few sprouts pop up the following season after I grew some plants from Australian seeds. This year, however, I have new PS growing wild literally all over my yard, in all sorts of places. Even my neighbor has petty spurge sprouts popping up between the seams of the astroturf that covers his backyard (gee, I wonder where those tiny airborne seeds originated?) As it happens, I have no skin issues of any sort this year. I haven't had a BCC outbreak since petty spurge knocked out two incidents and long-term vitamin C + DMSO took down another one. Hard to believe it's been 7 years since I started down this road with PS due to the great information on this forum. But the plant has really been a blessing to me. I'll probably end up mashing (some of) these plants up and making a tincture to keep over the winter just in case. You never know. |
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BobCA
43 Posts |
Posted - 04/16/2018 : 20:52:19
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| Please excuse my digression but is anyone using Polypodium Leucotomos known as PLE to help prevent sun damage? Recent studies shows it can actually help protect the DNA from mutating and becoming cancerous. I was taking nicotinamide but the scientific studies show PLE to be more effective. |
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Robiairty
1 Posts |
Posted - 07/08/2018 : 13:17:29
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| Agare did you use Ingenol mebutate |
Edited by - Robiairty on 07/08/2018 13:18:01 |
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agare
17 Posts |
Posted - 07/09/2018 : 05:32:47
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Ingenol mebutate is the active ingredient in petty spurge, so I was using this. But I was not using the commercial product Picato which uses an extract from petty spurge and advertises it is ingenol mebutate. I suspect that Picato utilizes a less concentrated form than would be supplied by using the sap itself.
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svanip
18 Posts |
Posted - 03/24/2021 : 19:51:23
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quote:
Originally posted by svanip
Hi Everyone,
Just a quick update 5 years on, absolutely no sign of and BCC the area is completely healed and has left no visible scar tissue. For me the petty spurge works brilliantly.
Scott
quote:
Originally posted by Grace2Go
Your bcc area looks great svanip! Thanks for posting the regular pictures of your progress.
My 3 little plants are growing very slowly, but as soon as one is big enough I'll be starting the sap treatment on my bcc.
quote:
Originally posted by svanip
Hi just thought I would put into action a live treatment for your information if anyone would like to see the results....
So far - 24th of March 2010 - I went for a Skin Check with my local GP I pointed out a legion I was concerned about "not seen by Dr" - A Shave biopsy taken following day of a 7 x 4 mm legion on Upper Left Lip region....
9 Days Pass 
Biopsy / Histology result was of a multifocal superficial BCC..
GP referred to plastic surgeon for surgical removal - surgeon not available to see me 12 weeks.....
After much deliberation and investigation I decided to try Petty Spurge treatment - it pretty much grows in every garden as a pest weed here......
6 April Image shows – Start "2 weeks post shave biopsy" - Then the following morning after initial application of the Milk/Sap.
Euphorbia Peplus - Petty Spurge - Radium Weed - Cancer Weed
SEEDS - try here www.beautanicals.com.au ( Service was very good )
WARNINGS:
This substance contains known carcinogens....  Try it at your own risk !!!
You may need to copy and paste this link.....
www.wildflowerfinder.org.uk/Flowers/S/Spurge" target="_blank">http://www.wildflowerfinder.org.uk/Flowers/S/Spurge(Petty)/Spurge(Petty).htm
Treatment:
What does the active ingredient do:
Basically the Sap starts to kill the Cancer Cells (Cell Necrosis) within hours of the application then the active components in the sap induce a secondary inflammatory response at the site of the application within 24-48 Hrs, which in turn generates tumor-specific antibodies to hopefully get rid of the balance of the nasty cells.... Something like that anyway - in very simple terms....
My treatment plan 12 Days twice a day application.....
Pre Treatment Image - 2 Weeks Post BCC Shave Biopsy
Me: svanip@hotmail.com
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First Day of Treatment !
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Day 2 approx 36 Hrs Post Euphorbia Peplus Sap/Latex Application - it is growing
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Day 2 Afternoon Update - Its drying out and not stinging so much..... 
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Day Six - Morning Image - sorry re the lack of weekend images. It was a very painful weekend but not unbearable - the scab had completely covered the inflamed areas and came off on several occasions. I do quite a bit of sport - ie cycling and swimming so with the sweating and being in the water for several hours the area was scab free. The area seems to have stopped growing and feels like it is calming down somewhat ie: less pain and less blistering scabbing etc -I am opting for a review after the 12 Day x twice a day application period which is a little more than most I have read about online using Euphorbia Peplus raw sap only - I will continue to apply until the scabbing has been resolved then rest and recovery. I do not wash the sap off and I have not covered the area -unless showering etc then I re apply and let it dry on the treatment area - The amount of sap I use is quite small - a tiny drop - maybe the size of a pin head or two. This seems to be an ample quantity to soak into the treatment area - the sap is quite watery and not very viscous - it flows very willingly and spreads out over the area rapidly - the activity of the sap appears to radiate out and around the original treatment area without any need to cover it completely be careful this is a very strong substance indeed - as you can see from the images. I noted that several people had stated the the treatment was not painful - well on the face it is quite painful and it burns for several hours, if you can imagine a mild acid or caustic burn - that is what it is similar too - for me anyway.... enjoy
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Day 6 of treatment....
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Day 7 Images - The area appears to be healing and feeling OK the scabbing is very thick and firm now - the treatment area has some skin flaking around the margin - I am still applying the raw sap to the top of the scab after showering etc - it is still burning, so I guess the treatment is still working......
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www.topicalinfo.org/forum/uploaded/svanip/2010412191653_Picture-7a.jpg" border="0">
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This afternoons shot of the crusty demon - was a mild burning sensation all day "as usual" no great change today !
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Morning of Day 8 - Feeling similar scab is quite thick still some mild stinging after application of raw sap - not unbearable though.
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Afternoon Day 8 - Its Itchy and annoying !
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Morning Day 9 went for a hard twilight bike ride last night a lot of sweating etc - so in the middle of the scab the dark area is a crater about 3mm deep which obviously washed out with the fluids. this was the location of the original BCC Site - Ewwwwww Gross .....
Image Insert:
www.topicalinfo.org/forum/uploaded/svanip/2010414193231_Day-9a.jpg" border="0">
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Afternoon Day 9 - Not much to report - its very crusty itchy and annoying - the scab is huge and very thick, you cant see it on the image really...
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Morning Day 10 - Went for a 2K swim last night - scab is still mainly intact due to attached beard I think - not much change to the area, it is tender and a little itchy quite a bit of new pink skin is visible - I use a prescription antibacterial cream called Bactroban 2% at night over the entire area - want to minimize any secondary infection after swimming etc.
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Afternoon Day 10 - Feeling OK at the moment not much pain at all today, scab is shrinking "with help" if it wasn't in such a prominent position you would barley know it was there
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Morning Day 13 after some sporting activities and shaving the large scabs came of with a smaller center piece from the original BCC site still remains... have stopped the application of the raw sap and am covering the area with Bactroban 2% to aid in healing the area... lets hope that the BCC is dead and gone !!! 
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Afternoon Day 13
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This is a close up of the site morning Day 13 v's Day 1 pre application..
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9.08 KBe-13ab.jpg
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Day 14 Scab came off and left area visible......Second image is a close up shot - not sure if the BCC is gone or still alive.....
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Afternoon Day 14
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Morning Day 15 Healing well.....
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Close Up Day 15
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Day 15 afternoon image
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Day 16 Morning Image (Vitamin E used over night)
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Close up Day 16
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Hi me again its now been 11 years on and still no sign af any BCC.
![]()
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Edited by - svanip on 03/24/2021 19:53:42 |
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svanip
18 Posts |
Posted - 03/24/2021 : 19:58:18
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Hi Everyone, 11 year update of area
Image Insert:
quote:
Originally posted by svanip
[quote]Originally posted by svanip
Hi Everyone,
Just a quick update 5 years on, absolutely no sign of and BCC the area is completely healed and has left no visible scar tissue. For me the petty spurge works brilliantly.
Scott
[quote]Originally posted by Grace2Go
Your bcc area looks great svanip! Thanks for posting the regular pictures of your progress.
My 3 little plants are growing very slowly, but as soon as one is big enough I'll be starting the sap treatment on my bcc.
[quote]Originally posted by svanip
Hi just thought I would put into action a live treatment for your information if anyone would like to see the results....
So far - 24th of March 2010 - I went for a Skin Check with my local GP I pointed out a legion I was concerned about "not seen by Dr" - A Shave biopsy taken following day of a 7 x 4 mm legion on Upper Left Lip region....
9 Days Pass
Biopsy / Histology result was of a multifocal superficial BCC..
GP referred to plastic surgeon for surgical removal - surgeon not available to see me 12 weeks.....
After much deliberation and investigation I decided to try Petty Spurge treatment - it pretty much grows in every garden as a pest weed here......
6 April Image shows – Start "2 weeks post shave biopsy" - Then the following morning after initial application of the Milk/Sap.
Euphorbia Peplus - Petty Spurge - Radium Weed - Cancer Weed
SEEDS - try here www.beautanicals.com.au ( Service was very good )
WARNINGS:
This substance contains known carcinogens.... Try it at your own risk !!!
You may need to copy and paste this link.....
www.wildflowerfinder.org.uk/Flowers/S/Spurge" target="_blank">http://www.wildflowerfinder.org.uk/Flowers/S/Spurge(Petty)/Spurge(Petty).htm
Treatment:
What does the active ingredient do:
Basically the Sap starts to kill the Cancer Cells (Cell Necrosis) within hours of the application then the active components in the sap induce a secondary inflammatory response at the site of the application within 24-48 Hrs, which in turn generates tumor-specific antibodies to hopefully get rid of the balance of the nasty cells.... Something like that anyway - in very simple terms....
My treatment plan 12 Days twice a day application.....
Pre Treatment Image - 2 Weeks Post BCC Shave Biopsy
Me: svanip@hotmail.com
Image Insert:
www.topicalinfo.org/forum/uploaded/svanip/20104831433_Day-1a.jpg" border="0">
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First Day of Treatment !
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Day 2 approx 36 Hrs Post Euphorbia Peplus Sap/Latex Application - it is growing
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www.topicalinfo.org/forum/uploaded/svanip/201048212124_Day-3a.jpg" border="0">
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Day 2 Afternoon Update - Its drying out and not stinging so much.....
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Day Six - Morning Image - sorry re the lack of weekend images. It was a very painful weekend but not unbearable - the scab had completely covered the inflamed areas and came off on several occasions. I do quite a bit of sport - ie cycling and swimming so with the sweating and being in the water for several hours the area was scab free. The area seems to have stopped growing and feels like it is calming down somewhat ie: less pain and less blistering scabbing etc -I am opting for a review after the 12 Day x twice a day application period which is a little more than most I have read about online using Euphorbia Peplus raw sap only - I will continue to apply until the scabbing has been resolved then rest and recovery. I do not wash the sap off and I have not covered the area -unless showering etc then I re apply and let it dry on the treatment area - The amount of sap I use is quite small - a tiny drop - maybe the size of a pin head or two. This seems to be an ample quantity to soak into the treatment area - the sap is quite watery and not very viscous - it flows very willingly and spreads out over the area rapidly - the activity of the sap appears to radiate out and around the original treatment area without any need to cover it completely be careful this is a very strong substance indeed - as you can see from the images. I noted that several people had stated the the treatment was not painful - well on the face it is quite painful and it burns for several hours, if you can imagine a mild acid or caustic burn - that is what it is similar too - for me anyway.... enjoy
Image Insert:
www.topicalinfo.org/forum/uploaded/svanip/201041120615_Day-6a.jpg" border="0">
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Day 6 of treatment....
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Day 7 Images - The area appears to be healing and feeling OK the scabbing is very thick and firm now - the treatment area has some skin flaking around the margin - I am still applying the raw sap to the top of the scab after showering etc - it is still burning, so I guess the treatment is still working......
Image Insert:
www.topicalinfo.org/forum/uploaded/svanip/2010412191653_Picture-7a.jpg" border="0">
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This afternoons shot of the crusty demon - was a mild burning sensation all day "as usual" no great change today !
Image Insert:
www.topicalinfo.org/forum/uploaded/svanip/20104131460_Picture-7b.jpg" border="0">
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Morning of Day 8 - Feeling similar scab is quite thick still some mild stinging after application of raw sap - not unbearable though.
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www.topicalinfo.org/forum/uploaded/svanip/201041320730_Day-8a.jpg" border="0">
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Afternoon Day 8 - Its Itchy and annoying !
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Morning Day 9 went for a hard twilight bike ride last night a lot of sweating etc - so in the middle of the scab the dark area is a crater about 3mm deep which obviously washed out with the fluids. this was the location of the original BCC Site - Ewwwwww Gross .....
Image Insert:
www.topicalinfo.org/forum/uploaded/svanip/2010414193231_Day-9a.jpg" border="0">
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Afternoon Day 9 - Not much to report - its very crusty itchy and annoying - the scab is huge and very thick, you cant see it on the image really...
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www.topicalinfo.org/forum/uploaded/svanip/201041525521_Day-9b.jpg" border="0">
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Morning Day 10 - Went for a 2K swim last night - scab is still mainly intact due to attached beard I think - not much change to the area, it is tender and a little itchy quite a bit of new pink skin is visible - I use a prescription antibacterial cream called Bactroban 2% at night over the entire area - want to minimize any secondary infection after swimming etc.
Image Insert:
www.topicalinfo.org/forum/uploaded/svanip/2010415195116_Day-10a.jpg" border="0">
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Afternoon Day 10 - Feeling OK at the moment not much pain at all today, scab is shrinking "with help" if it wasn't in such a prominent position you would barley know it was there
Image Insert:
www.topicalinfo.org/forum/uploaded/svanip/20104161310_Day-10b.jpg" border="0">
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Morning Day 13 after some sporting activities and shaving the large scabs came of with a smaller center piece from the original BCC site still remains... have stopped the application of the raw sap and am covering the area with Bactroban 2% to aid in healing the area... lets hope that the BCC is dead and gone !!!
Image Insert:
www.topicalinfo.org/forum/uploaded/svanip/2010418194643_Day-13a.jpg" border="0">
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Afternoon Day 13
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This is a close up of the site morning Day 13 v's Day 1 pre application..
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www.topicalinfo.org/forum/uploaded/svanip/201041820412_Picture-13ac.jpg" border="0">
9.08 KBe-13ab.jpg
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Day 14 Scab came off and left area visible......Second image is a close up shot - not sure if the BCC is gone or still alive.....
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Afternoon Day 14
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Morning Day 15 Healing well.....
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Close Up Day 15
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Day 15 afternoon image
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Day 16 Morning Image (Vitamin E used over night)
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Close up Day 16
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Edited by - svanip on 03/24/2021 20:19:37 |
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anivoc
668 Posts |
Posted - 03/25/2021 : 15:47:59
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| Awesome pictorial! Congratulations on whooping that BCC's butt and thanks for photo documenting your journey! |
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fRomance
81 Posts |
Posted - 04/02/2021 : 01:38:40
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| You nailed it, congratulations! |
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Topic |
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Petty Spurge Herb sap for skin cancers
