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mark72
22 Posts |
 Posted - 05/08/2015 : 17:50:12
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joekimbell
1 Posts |
Posted - 05/13/2015 : 09:34:37
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| cannabis oil was indeed wonderful and very effective in treating cancer' if not for the government and their so called rules in regulating cannabis my wife would have still been alive. thanks to the newly policy for legalizing cannabis else i would have still lost my daufgter to kidney cancer, i was really touched and surprised when i watch lots of documentary on how cannabis oil had helped lot of people whom their family members never thought they could make it after undergoing several ''Chemo'' from the dept of my heart i must say a word of appreciation to DrThomas Fandez for the timely intervention in the life of my daughter suffering from Kidney Cancer. as i am writing this testimony on this Blog my daughter is so strong and healthy in spite he hasn't completed the total Dosage.' for your cannabis and medical consultation try and get in touched with him on his email:dr.thomasfendazhelp@dr.com, he can help and enlightened you more. thanks, good luck. |
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marg
3 Posts |
Posted - 05/19/2015 : 06:51:43
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| I'm hoping there's still someone on this forum who's selling petty spurge seeds, hopefully from organic plants. Also wonder if starting them now would be of any use as they would still be very small plants when the summer weather comes. Does anyone know if they can survive the summer in Eugene, OR? Thanks so much for your help. |
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BobCA
43 Posts |
Posted - 05/19/2015 : 09:03:21
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The good news is that Petty Spurge does grow in Oregon. http://www.pnwflowers.com/flower/euphorbia-peplus
I was going to try seeds but noticed they are growing wild throughout my yard. This year was a particularly good bloom. My climate in CA is a little more arid than yours but before going through the hassle of getting seeds and trying to get them to germinate look around for plants. They are small and grow in shallow soil, between rocks, etc.
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marg
3 Posts |
Posted - 05/19/2015 : 11:22:03
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quote:
Originally posted by BobCA
The good news is that Petty Spurge does grow in Oregon. http://www.pnwflowers.com/flower/euphorbia-peplus
I was going to try seeds but noticed they are growing wild throughout my yard. This year was a particularly good bloom. My climate in CA is a little more arid than yours but before going through the hassle of getting seeds and trying to get them to germinate look around for plants. They are small and grow in shallow soil, between rocks, etc.
Hi, Bob. Thanks so much for your reply. I have already looked around for it. You're very blessed that you have it in your yard. If it weren't so hard to ship plants I'd offer to buy some from you. |
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BobCA
43 Posts |
Posted - 05/19/2015 : 12:10:58
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| If you can find a way to ship plants I'd give you some. If you know anyone who drives to the Bay Area I'd be happy to meet them and deliver some plants. I'll probably have them until mid summer. Once the weather gets really hot they don't do as well. |
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marg
3 Posts |
Posted - 05/26/2015 : 06:44:13
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| Thanks so much for the offer, BobCA. Unfortunately I don't know anyone driving there and I don't have a car. (I'm 70 & don't drive anymore.) If I find a way to ship plants it would be great to get some from you. |
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Brigid
68 Posts |
Posted - 05/27/2015 : 14:08:54
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quote:
Originally posted by mark72
http://www.washingtonpost.com/wp-srv/special/metro/urban-jungle/pages/110419.html
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018636/
The Efficacy of Dandelion Root Extract in Inducing Apoptosis in
Drug-Resistant HumanMelanoma Cells.
Received 22 June 2010; Revised 12 November 2010; Accepted 8 December 2010
3. Results
3.1. Effect of Dandelion Root Extract (DRE) on Human Melanoma Cell Viability. In order to investigate whether Dandelion Root Extract (DRE) reduced cell viability in
human melanoma cells, the A375 cells were treated with 1, 2.5, and 5 mg/mL concentrations of DRE. DRE was found to reduce cell viability in a dose-dependent fashion,
over time, in A375 melanoma cells as was measured by WST-1 assay. Based on metabolic activity of A375s, it was confirmed that treatment at 2.5mg/mL DRE resulted in 50% reduction in cell viability against control within 24 hours (Figure 1(a)). After cells were imaged with Hoechst dye, it was found that by 48 hours there was a clear
induction of apoptosis at concentrations above 2.5mg/mL (Figure 1(b)), as distinguished by brightly stained nuclei and Using the effective and subeffective doses, we sought to
confirm that apoptosis in A375 cells was indeed induced, using the Annexin-V binding assay. The assay confirms that by 48 hours the phosphatidyl serine has flipped from the
inner leaflet of the plasma membrane to the outer leaflet after treatment with 2.5mg/mL DRE (Figure 1(c)).
3.2. Evaluation of DRE Toxicity onNormalHuman Fibroblasts. With DRE having proven its efficacy in successfully killing this aggressive, chemoresistant form of skin cancer, DRE toxicity on normal cells had to be evaluated.
4. Discussion
Dandelion Root Extract (DRE) has thus far been used in traditional medicine as a detoxifying agent for digestive disorders, for lung, breast, and uterine tumours [2], and
most interestingly, to treat chronic diseases of the skin [4].
However, there has been little scientific advancement made in this field with regard to the effect of dandelion root extract on cancer, and even more so on chemoresistant,
human malignant melanoma skin cancer. Previous work with Taraxacum has not provided much mechanistic detail with regards to apoptosis induction, instead highlighting its antioxidant and anti-inflammatory effects. In this study of human melanoma cells, we show that Dandelion Root Extract (DRE) is more than a worthy chemopreventative, it is fast-acting, nontoxic, and therefore specific in its targeting.
It was confirmed that treatment at 2.5mg/mL DRE resulted in 50% reduction in cell viability against control within 24 hours. After cells were imaged with Hoechst dye, it was found that by 48 hours there was a clear induction of apoptosis at concentrations above 2.5mg/mL DRE resulted in 90% reduction in cell viability, and after 72hours at 95% of melanoma cells Were destroyed inducting Apoptosis.
The treatment continued for 92 hours.
I have decided to take a calculated risk. I have to treat my small spot for 92 hours 2 to 3 times per day, and after rest and tread for healing.
It is not a very good idea to treat more than a spot, and greater the spot bigger the risk, because (DRE toxicity on normal cells had to be evaluated.)
Do not do it. I’m responsible for my actions. If anybody decides to do it, then you take your risk, and you, and only you are responsible for your ACTIONS.
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judo
33 Posts |
Posted - 06/11/2015 : 05:41:01
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| Can anyone recommend whether to carry on treating with PS or just stop and see what happens to the scab please? The scab is about 2mm high now, quite prominent! Diagnosed as AK a year ago, prescribed Aldara but i didn't use it. Changed my diet and treated topically with ACV and thought I'd beaten it but then it just kept scabbing up. I have treated it twice a day with PS for 8 days, and now have had 5 days off - the scab has changed colour from a sort of puss colour to dark red, blood colour. Any thoughts? Thanks. |
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BobCA
43 Posts |
Posted - 06/11/2015 : 09:06:38
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| Judo- I can only speak from my research and experience but I would not continue apply Petty Spurge. Petty Spurge contains Ingenil Mebutate which is the active ingredient in Picato. I use the Petty Spurge just like Picato. Once a day for 3 days. Ingenol Menutate works by attacking cells that divide quickly and often which can be cancer or cells that are regenerating. |
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srains99
13 Posts |
Posted - 06/11/2015 : 09:25:23
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| Agree,when my scab change, I stopped using it. PS saved me from Mohs surgery. PS healed well. Left a healed spot with a small indentation that seemed to be filling in over time |
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judo
33 Posts |
Posted - 06/11/2015 : 10:24:02
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Thank you both for your replies. The scab feels like it has liquid inside it, since I started applying PS I've tried to keep it dry so it's almost like it has a bubble/puddle of liquid/pus underneath a thin dry scab.
Wish I could let a pic but I can't get them to upload for some reason. |
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judo
33 Posts |
Posted - 06/11/2015 : 10:27:24
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| I really want to have a shower and let the water run over my head and wash it off. I think the water would simply wash it off. |
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BobCA
43 Posts |
Posted - 06/11/2015 : 12:11:09
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| judo - By all means take a shower. The water will soften the scab but I wouldn't pick it off. Let it heal from the inside out and fall off. I would, and this is what my dermatologist recommends, after the shower cover the scab with a little vaseline or some other ointment. It will keep it moist and help it heal. No need to cover it. |
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BobCA
43 Posts |
Posted - 06/11/2015 : 12:15:58
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| Niacinamide - In case others have not heard a recent study coming out of New Zealand found that taking a daily supplement of Niacinamide (nicotinamide) a form of Vitamin B3 reduced the recurrence of Actinic Keratosis by over 60%. The cost of the supplement is cheap, less than $10/month. My dermatologist says he sees no harm in trying. I take 500mg daily, no side effects. If you do try it make sure you get the Niacinamide not the common Niacin. |
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BobCA
43 Posts |
Posted - 06/11/2015 : 14:33:34
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| Judo-one more thing. Petty Spurge should be applied and left unaltered for 6 hours. After 6 hours you can wash the area. The topical Ingenol Mebutate works at the cellular level and will attack any abnormal squamous and basal cells. After it kills the cell it will promote a strong immune response. Rather than over apply I would apply once every day for three days and let it react and heal. I would then reapply in a month or two. This way you will catch any cells you might have missed. Zyclara works by a different mechanism but is also effective, it just takes a lot longer. Best of luck. |
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judo
33 Posts |
Posted - 06/11/2015 : 23:52:11
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Thanks so much for the information Bob, really interesting. I did shower it before bed last night and to my surprise it didn't float off, afterwards I dabbed it with some tissue to dry it and lots of pus came out, I deflated it a bit by doing so, and a small part of the scab came off but most is still intact.
Will report back in a day or two to let you know the progress |
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cheryl21
19 Posts |
Posted - 06/13/2015 : 17:05:31
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Hi Judo,
The results from Petty Spurge are fantastic if you don't allow the scab to get wet, don't put anything on it, leave it alone and just let the scab fall off of its own accord. If you do this the area heals up without leaving any trace of a scar - you can't even tell where you used it. I have been using it for years and got my instructions originally from a doctor.
You should have a good result with what you are doing.
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BobCA
43 Posts |
Posted - 06/13/2015 : 17:23:41
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| Interesting Comment. My dermatologist says leave it on for 6 hours or overnight but then washing is fine. He always recommends never letting a scab get crusty. Apply ointment and it will heal in 3 days. Best of luck. |
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judo
33 Posts |
Posted - 06/17/2015 : 06:50:47
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Many thanks Cheryl, Bob. I have a thin scab covering the area now and the itching has subsided somewhat too. Hoping the scab will come off soon as it looks similar to the one that was there before I started the PS.
What ointment did you use Bob?
Is there a trick to attaching pictures on here, it would be nice to share the results for others to see too..? |
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BobCA
43 Posts |
Posted - 06/17/2015 : 07:14:25
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| Hi Judo - my Dermatologist and surgeon both recommend petrolatum or basically Vaseline but neosporin or aquafor work well and are slightly antibiotic. |
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judo
33 Posts |
Posted - 07/13/2015 : 05:44:06
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| Hi again, just an update for you all. The scab eventually came off, i started to put a drop of olive oil (fairly harmless stuff) on it once or twice a day and within a week or so it came off but did leave a little bit left behind, that came off last Friday. For a couple of days i was scab less but now the little one seems to have bubbled/bled slightly and formed an even smaller one...i'm guessing that I might need to treat this with some more spurge? Any suggestons Bob? |
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BobCA
43 Posts |
Posted - 07/13/2015 : 08:31:46
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I wouldn't recommend using any ore Spurge until the lesion has healed completely. The Ingenol Mebutate will attack the good cells that are trying to heal as these cells are also rapidly dividing. Let it heal first the in another month you can apply not spurge. Not sure about the Olivr oil. The goal is to keep the scab moist.
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svanip
18 Posts |
Posted - 07/14/2015 : 03:30:35
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Hi Everyone,
Just a quick update 5 years on, absolutely no sign of and BCC the area is completely healed and has left no visible scar tissue. For me the petty spurge works brilliantly.
Scott
quote:
Originally posted by Grace2Go
Your bcc area looks great svanip! Thanks for posting the regular pictures of your progress.
My 3 little plants are growing very slowly, but as soon as one is big enough I'll be starting the sap treatment on my bcc.
quote:
Originally posted by svanip
Hi just thought I would put into action a live treatment for your information if anyone would like to see the results....
So far - 24th of March 2010 - I went for a Skin Check with my local GP I pointed out a legion I was concerned about "not seen by Dr" - A Shave biopsy taken following day of a 7 x 4 mm legion on Upper Left Lip region....
9 Days Pass 
Biopsy / Histology result was of a multifocal superficial BCC..
GP referred to plastic surgeon for surgical removal - surgeon not available to see me 12 weeks.....
After much deliberation and investigation I decided to try Petty Spurge treatment - it pretty much grows in every garden as a pest weed here......
6 April Image shows – Start "2 weeks post shave biopsy" - Then the following morning after initial application of the Milk/Sap.
Euphorbia Peplus - Petty Spurge - Radium Weed - Cancer Weed
SEEDS - try here www.beautanicals.com.au ( Service was very good )
WARNINGS:
This substance contains known carcinogens....  Try it at your own risk !!!
You may need to copy and paste this link.....
www.wildflowerfinder.org.uk/Flowers/S/Spurge" target="_blank">http://www.wildflowerfinder.org.uk/Flowers/S/Spurge(Petty)/Spurge(Petty).htm
Treatment:
What does the active ingredient do:
Basically the Sap starts to kill the Cancer Cells (Cell Necrosis) within hours of the application then the active components in the sap induce a secondary inflammatory response at the site of the application within 24-48 Hrs, which in turn generates tumor-specific antibodies to hopefully get rid of the balance of the nasty cells.... Something like that anyway - in very simple terms....
My treatment plan 12 Days twice a day application.....
Pre Treatment Image - 2 Weeks Post BCC Shave Biopsy
Me: svanip@hotmail.com
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First Day of Treatment !
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Day 2 approx 36 Hrs Post Euphorbia Peplus Sap/Latex Application - it is growing
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Day 2 Afternoon Update - Its drying out and not stinging so much..... 
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Day Six - Morning Image - sorry re the lack of weekend images. It was a very painful weekend but not unbearable - the scab had completely covered the inflamed areas and came off on several occasions. I do quite a bit of sport - ie cycling and swimming so with the sweating and being in the water for several hours the area was scab free. The area seems to have stopped growing and feels like it is calming down somewhat ie: less pain and less blistering scabbing etc -I am opting for a review after the 12 Day x twice a day application period which is a little more than most I have read about online using Euphorbia Peplus raw sap only - I will continue to apply until the scabbing has been resolved then rest and recovery. I do not wash the sap off and I have not covered the area -unless showering etc then I re apply and let it dry on the treatment area - The amount of sap I use is quite small - a tiny drop - maybe the size of a pin head or two. This seems to be an ample quantity to soak into the treatment area - the sap is quite watery and not very viscous - it flows very willingly and spreads out over the area rapidly - the activity of the sap appears to radiate out and around the original treatment area without any need to cover it completely be careful this is a very strong substance indeed - as you can see from the images. I noted that several people had stated the the treatment was not painful - well on the face it is quite painful and it burns for several hours, if you can imagine a mild acid or caustic burn - that is what it is similar too - for me anyway.... enjoy
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Day 6 of treatment....
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Day 7 Images - The area appears to be healing and feeling OK the scabbing is very thick and firm now - the treatment area has some skin flaking around the margin - I am still applying the raw sap to the top of the scab after showering etc - it is still burning, so I guess the treatment is still working......
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This afternoons shot of the crusty demon - was a mild burning sensation all day "as usual" no great change today !
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Morning of Day 8 - Feeling similar scab is quite thick still some mild stinging after application of raw sap - not unbearable though.
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Afternoon Day 8 - Its Itchy and annoying !
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Morning Day 9 went for a hard twilight bike ride last night a lot of sweating etc - so in the middle of the scab the dark area is a crater about 3mm deep which obviously washed out with the fluids. this was the location of the original BCC Site - Ewwwwww Gross .....
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Afternoon Day 9 - Not much to report - its very crusty itchy and annoying - the scab is huge and very thick, you cant see it on the image really...
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Morning Day 10 - Went for a 2K swim last night - scab is still mainly intact due to attached beard I think - not much change to the area, it is tender and a little itchy quite a bit of new pink skin is visible - I use a prescription antibacterial cream called Bactroban 2% at night over the entire area - want to minimize any secondary infection after swimming etc.
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Afternoon Day 10 - Feeling OK at the moment not much pain at all today, scab is shrinking "with help" if it wasn't in such a prominent position you would barley know it was there
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Morning Day 13 after some sporting activities and shaving the large scabs came of with a smaller center piece from the original BCC site still remains... have stopped the application of the raw sap and am covering the area with Bactroban 2% to aid in healing the area... lets hope that the BCC is dead and gone !!! 
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Afternoon Day 13
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This is a close up of the site morning Day 13 v's Day 1 pre application..
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Day 14 Scab came off and left area visible......Second image is a close up shot - not sure if the BCC is gone or still alive.....
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Afternoon Day 14
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Morning Day 15 Healing well.....
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Close Up Day 15
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Day 15 afternoon image
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Day 16 Morning Image (Vitamin E used over night)
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Close up Day 16
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BobCA
43 Posts |
Posted - 07/14/2015 : 06:29:31
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Svanip - That is great news and thanks for the followup. A new study has come out of New Zealand on the use of Niacinamide to significantly reduce the recurrence of Actinic Keratosis (AKs). Niacinamide is the -amide form of vitamin B3. The study has subjects taking an oral dose of 500mg/day. This stuff is really cheap, less than $10/month, and readily available. Not to be confused with Niacin which is also B3. It sometimes goes by the name Nicotinamide.
I am also using Niacinamide serum, a small tab goes a long way, and works by promoting healthy regeneration of skin cells as well as an inhibitor to UV light damage. According to studies it can help the cell's DNA resist mutational damage from the sun's UV light. Niacinamide serum has been used medically to even out skin tone as well as heal acne scars.
You'll need to hunt around a little for lotions that contain Niacinamide but I have found it on Amazon http://www.amazon.com/gp/product/B00J5N0Y4U?refRID=2GDVMYEESA5JB9F3CD58&ref_=pd_ys_sf_s_rp_a1_1_p |
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BobCA
43 Posts |
Posted - 07/14/2015 : 06:43:34
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judo - Sorry for all the typos on my previous reply as I was on my mobile and didn't recheck my typing. Let me please elaborate further.
Ingenol Mebutate, the active ingredient in Petty Spurge and Picato, works by attacking cells that are dividing rapidly. Cancer cells as well as new cells repairing a wound divide quickly. The risk of using Petty Spurge over too long a period of time or in this case, on a lesion that may still be healing, is that it can attack the good cells trying to divide and form new skin. I would hold off using any additional Petty Spurge until one month after the wound has completely healed. Petty Spurge will not help this lesion heal. If the lesion seems to take a long time to heal I would get it checked out. Remember, Ingenol Mebutate is prescribed for Actinic Keratosis and not for squamous nor basal cell carcinoma but many users here have had good results using it on both squamous and basal cell carcinomas. The risk is that with squamous cell carcinoma it can metastasize (spread). We certainly want to catch it before that ever happens.
Regarding the use of Olive oil on a scab - My only concern would be that the olive oil would not provide that topical barrier like a petrolatum (vaseline) and may get absorbed. A bigger concern would be that it could grow bacteria because unlike petrolatum it is organic. If you have an open lesion I would pick up a small tube of aquaphor or neosporin. My surgeon and dermatologist no longer recommend these as they found some people can be alergic and the antibiotic benefit over petrolatum is minimal. |
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judo
33 Posts |
Posted - 07/14/2015 : 07:26:19
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Thank you Bob and svanip, both very kind and useful comments. The PS has definitely done some good, I seem to back to where I was when this initially flared up about 18mnths ago, just a little scab that i accidentally brush off after a shower. To all intents and purposes it does look healed but I'll hang on a bit longer before re-treating. I think that this particular part was so well covered with a scab before that the PS may not have penetrated it enough.
Svanip's treatment was over quite a long time period, I treated for 7-8 days, a couple of drops a day, so maybe not long enough? |
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BobCA
43 Posts |
Posted - 07/14/2015 : 07:54:43
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| judo- If it is a tiny superficial scab that easily picks off it sounds like you may be ready for another treatment of PS. Remember that Ingenol Mebutate works at the cellular level and the small amount we put on will find it's way to the remote cells. I understand people have used it PS many ways regarding duration, application, and some even cover it with tape. I use it the way Picato is prescribed. Once a day for three days. The strongest reaction will come within the first 24-48 hours. Now, with that said, Picato is prescribed for AK and not basal or squamous cell carcinomas so it could be the three day treatment is valid for the most superficial of lesions. Ingenol Mebutate does not get absorbed into the body so your liver and other organs are safe from overuse so the only risk I can see is at what point has it killed all of the cancer and started to react with the normal healing cells. Be aware of that balance and you should be fine. Remember, you can always retreat as many times as it takes. |
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judo
33 Posts |
Posted - 07/14/2015 : 08:07:23
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Thanks Bob, it is very much superficial so I feel much more comfortable about giving it another go. We have some growing in our garden so I'll start another round on the basis that Picato is prescribed and keep you up to date.
Best wishes |
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judo
33 Posts |
Posted - 07/22/2015 : 01:27:13
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| Ok, I put the first drop of PS on last Tuesday evening (just one drop), same on Wed and Thurs, so once a day for 3 days. By the second day the scab had started to grow out an up and continued to do so fr a few days, but still smaller than my initial treatment. Again, although it's was quite red, it was also yellow with puss (that's what it looked like anyway) and it would leak occasionally, especially if I got it wet in the shower. This morning it was pretty loose so I moved it with a q tip (moved, not picked) and it slid off. Underneath it still looks a bit messy but not as bad as the scab thing. Guess I'll just leave it alone now and see what happens, will report back in a week or so with another update. |
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Thomas Haugen
94 Posts |
Posted - 07/23/2015 : 19:46:32
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I have petty spurge seeds for anyone in the USA.
The tiny plants don't seem to like transplanting so maybe best to grow seeds outside in damp, partly shady to shady garden ares. Two months or more to reach a usable 4" size.
Tom |
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Thomas Haugen
94 Posts |
Posted - 08/04/2015 : 16:44:59
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| The seeds are free, just email me through this forum and I'll email you my address. Then send me a padded SASE and I'll mail you the seeds, probably some time later in August. Can't hurry Nature. |
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judo
33 Posts |
Posted - 08/05/2015 : 00:18:44
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Ok so I left it for a week or two and on Monday the last small scab came off, hooray. Unless you knew something was there before, you'd be hard pushed to identify the area. Fingers crossed it stays this way now! For those that might need seeds or a small plant, I live in North Essex, England, so just get in touch if required.
Thanks again to everyone on here who helped out :) |
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BobCA
43 Posts |
Posted - 08/05/2015 : 06:00:42
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judo, that is great to hear. Now perhaps you are ready to take the next step, prevention. Ingenol Mebutate, the active ingredient in Petty Spurge, is prescribed also as a prophylaxis to Actinic Keratosis. We have used it here to remove AKs as well as some Basal and Squamous carcinomas. If you take a few drops of petty spurge and rub it over an area likely to have developing AKs, like forehead, arm or ear, once a day for 3 days, any hidden AKs or cancerous lesions will react. This is how my Dermatologist recommends I stay clear of developing cancers. Treat it once a year or every 6 months until you no longer have any reaction.
The latest therapy I have been reading a lot about is Niacinamide. This is taken orally as a vitamin, 500mg, and also applied topically. It has been touted as a "miracle" aging serum as it removes small wrinkles and lines but for us it stimulates anti tumor cells and helps prevent DNA mutations at the cellular level. Research shows that it can keep AKs from recurring by up to 60%. Although Niacinamide is converted from Niacin B3 you want to take the Niacinamide form. Taking too much Niacin can cause skin flushing and itching. |
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Rico818
3 Posts |
Posted - 08/28/2015 : 13:05:35
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Hi all! I am new to the forum. I have been hearing good things about petty spurge sap on skin cancers. I understand that the plant is considered an invasive species in warmer climates of the U.S.. It does seem strange to me that there are no sources for seeds in the U.S. amongst the people who have had good results from the sap on skin cancers.
Because I am new here, I cannot email T. Haugen for his address to get seeds. I am sending for seeds from Australia (Fair Dinkum Seeds) but am leery of the possibility of fakes. If you have seeds that are definitely from Euphorbia Peplus, please post here or email ricklawhon@live.com. Thanks so much |
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BobCA
43 Posts |
Posted - 08/29/2015 : 07:28:17
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Hi Rico818 and welcome. I believe if you click on the user id to the left of the post you will get an option to email the user. I have not tried this however but I have seen the option.
I had wanted to make seeds available but they are so tiny I couldn't figure out a way to harvest them. Then I read here that, I think it was Mr. Haugen, he just sends the entire dried plant and lets you harvest the seeds. For me the seeds are not obvious so if anyone has harvested seeds please let me know how to do it. I'd be happy to send them. The seeds about the size of sesame seed.
My final plants are now dried and not producing sap. The ones in the summer shade bloomed last and lasted the longest. The larger ones (about 10" high) remain as a dried plant, the smaller ones just dry up and go away. I probably won't get another bloom unit late winter/early spring.
Just an aside, it is easy to harvest the sap but it needs to be kept cold and has a short shelf life. I would not recommend buying the sap unless it is shipped cold and guaranteed.
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Rico818
3 Posts |
Posted - 08/30/2015 : 17:51:47
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Hello all. I am so pleased to have had 4 responses already! Thank you! I have not confirmed any additional source yet beyond those that I am expecting from Australia soon. I would like to get seeds from more than one source. I have read that plants grown in different areas, may have different properties and on the chance that the species might have been misidentified by the grower.
I am new to the forum and do not have the ability to contact members by email until I complete some number of posts here. This is #2!!
Please keep the seed or possibly bare root plant offers coming. I will gladly compensate you any agreeable amount. Thank you!!!
ricklawhon@live.com I'M IN Missouri |
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Rico818
3 Posts |
Posted - 08/30/2015 : 19:18:53
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Hello all. I am so pleased to have had 4 responses already! Thank you! I have not confirmed any additional source yet beyond those that I am expecting from Australia soon. I would like to get seeds from more than one source. I have read that plants grown in different areas, may have different properties and on the chance that the species might have been misidentified by the grower.
I am new to the forum and do not have the ability to contact members by email until I complete some number of posts here. This is #2!!
Please keep the seed or possibly bare root plant offers coming. I will gladly compensate you any agreeable amount. Thank you!!!
ricklawhon@live.com I'M IN Missouri |
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srains99
13 Posts |
Posted - 08/31/2015 : 04:57:54
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| Contact Will atwwill1227@aol.com. he posted his contact info on the previous page. He lives in the North East and he is the person I got my plantern from. Real nice guy, very helpful. The plant saved me from Mohs surgery. |
Edited by - srains99 on 08/31/2015 04:58:38 |
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Rico818
3 Posts |
Posted - 08/31/2015 : 09:52:14
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| Thanks srains99! I did get a message from wwill and he says to email in a month. He may have some growth with seeds by then. |
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agare
17 Posts |
Posted - 09/06/2015 : 03:26:08
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quote:
Originally posted by mrosen
Just following up on some of my previous posts wondering if anyone out there knows of anyone succesfully using PS on Basal Cell Carcinoma that was a more infiltrative type? I noticed that svanip had success and his was multifocal superfiscial BCC,My BCC area looks different and covers a larger area maybe the size of a nickle where there is AK and now BCC.Also i believe Waverider has had success on superfiscial BCC?Its hard to get info as some have left forum and i dont know what outcomes were and weather they new if they were treating a more invasive BCC with the PS? MY BCC area is very angry right now i think all this stress and anxiety is making it worse...i need to start moving forward on some type of treatment and may start VITC paste(dmso?)at least i think it may hold BCC area till i can get some PS or get MOHS (which i am trying to avoid)The iodine looks interesting also...My BCC goes around my left nasolabial fold which is under left nostral(and against)and wraps around left side. Mrosen
From mrosen's description, I have an almost identical BCC - invasive nodular very close to my nose, beside it and just underneath it - two nodules close together pearly white nodules each 5mm in diameter. I wonder whether PS was successful in treating this. Several years ago I cured a large squamous cell carcinoma on my chest - 3cm by 3cm. I assumed then that any new skin cancer, apart from melanoma, could be treated the same way. Based on the biopsy, my doctor ruled out PS, which he had tacitly approved of previously. I am booked in for an operation in less than two weeks, but decided to put PS on my nose anyway. Now it is red and painful, as it should be and I wonder what the surgeon will think if I turn up for the operation like this. I read that Curaderm can successfully treat invasive nodular BCCs, although it takes a lot longer, but this does not seem to have been the case with mrosen. I guess I am tossing up whether to cancel the operation and continue with PS for at least one more triple dose in about a month, and then if as expected it is not cured, try some Curaderm to attempt to finish it off. Or just go ahead with the operation. I would really like to hear mrosen's views, but really anyone with experience in this.Agare. |
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BobCA
43 Posts |
Posted - 09/06/2015 : 11:49:38
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Hi Agare,
I enjoyed your post because you mentioned Curaderm BEC5 which I was unaware of. I did some research since I am getting very familiar with PS and it mechanisms on cancer cells.
First off, I wanted to clarify that were diagnosed by a biopsy that you have BCC on your face and that your surgeon has advised surgery and not topicals?
I'm going to assume, which is always dangerous, that he is advising surgery because it is maybe a little deeper than surface and because the only clinically approved method to remove 98% of BCC and SCC is surgery. Some derms are now using light treatments with good success but no derm is using a topical, yet.
With that said Curaderm BEC5 shows great promise by killing cancer cells (apoptosis) while leaving normal cells unaffected. However, it is about $120-$150US per tube and it takes twice a day for 8 weeks. In a recent clinical trial 8 weeks 78% people showed success after 8 weeks and further treatment is projected to result in better results. BEC5 kills cancer cells but not not invoke an strong immune response like PS.
Petty Spurge has the active ingredient Ingenol Mebutate. This is is also found in the FDA approved topical called Picato. It is only approved for AK but many users, myself included, have had great results on surface BCC and SCC. It works by also causing cell death but also invokes a stroke immune response further destroying cancer cells. Think of it as chemo with immunotherapy in one does. The real advantage to PS is you only need to use it once a day for 3 days. You can find it growing wild in the Euphorbia Peplus (Petty Spurge) but if you need to buy it as Picato is $900US per treatment.
The other topical, Imiquimod, invokes a strong immune response which attacks the rapidly dividing cells. Cheaper as it is generic now but takes 8-12 weeks to work.
As to you other questions on treating vs surgery; without knowing why your surgeon says surgery is required it is difficult to weigh in. It could be as simple as he can not take the risk by allowing you to self treat and the cancer spreads. The biggest risk for all cancers is that it has metastasized. Scientist are now learning that it is more a function of the type of genetic mutation that causes rapid tumor growth and metastasis than anything else. That is why some prostate cancers stay local and grow slowly while some will metastasize quickly. Your doctor probably wants to make sure he got it all, although that is not 100%, and he can not recommend something that is not yet approved.
Bets of luck, please keep us posted. Bob
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agare
17 Posts |
Posted - 09/06/2015 : 19:36:38
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quote:
Originally posted by BobCA
Hi Agare,
I enjoyed your post because you mentioned Curaderm BEC5 which I was unaware of. I did some research since I am getting very familiar with PS and it mechanisms on cancer cells.
First off, I wanted to clarify that were diagnosed by a biopsy that you have BCC on your face and that your surgeon has advised surgery and not topicals?
I'm going to assume, which is always dangerous, that he is advising surgery because it is maybe a little deeper than surface and because the only clinically approved method to remove 98% of BCC and SCC is surgery. Some derms are now using light treatments with good success but no derm is using a topical, yet.
With that said Curaderm BEC5 shows great promise by killing cancer cells (apoptosis) while leaving normal cells unaffected. However, it is about $120-$150US per tube and it takes twice a day for 8 weeks. In a recent clinical trial 8 weeks 78% people showed success after 8 weeks and further treatment is projected to result in better results. BEC5 kills cancer cells but not not invoke an strong immune response like PS.
Petty Spurge has the active ingredient Ingenol Mebutate. This is is also found in the FDA approved topical called Picato. It is only approved for AK but many users, myself included, have had great results on surface BCC and SCC. It works by also causing cell death but also invokes a stroke immune response further destroying cancer cells. Think of it as chemo with immunotherapy in one does. The real advantage to PS is you only need to use it once a day for 3 days. You can find it growing wild in the Euphorbia Peplus (Petty Spurge) but if you need to buy it as Picato is $900US per treatment.
The other topical, Imiquimod, invokes a strong immune response which attacks the rapidly dividing cells. Cheaper as it is generic now but takes 8-12 weeks to work.
As to you other questions on treating vs surgery; without knowing why your surgeon says surgery is required it is difficult to weigh in. It could be as simple as he can not take the risk by allowing you to self treat and the cancer spreads. The biggest risk for all cancers is that it has metastasized. Scientist are now learning that it is more a function of the type of genetic mutation that causes rapid tumor growth and metastasis than anything else. That is why some prostate cancers stay local and grow slowly while some will metastasize quickly. Your doctor probably wants to make sure he got it all, although that is not 100%, and he can not recommend something that is not yet approved.
Bets of luck, please keep us posted. Bob
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agare
17 Posts |
Posted - 09/06/2015 : 19:38:43
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Hi Bob,
Thank you for your detailed reply. Yes, I had a biopsy, and this was the finding:
SPECIMEN:
Right nasolabial area: A 3mm core of skin 2mm deep. Processed whole.
MICROSCOPY:
The section of skin shows invasive nodulocystic aggregates of basaloid tumour cells. The tumour cells have enlarged, hyperchromatic nucei and show palisading of peripheral nuclei. The tumour extends to the deep edge of the specimen.
CONCLUSION:
Right nasolabial area: Nodular basal cell carcinoma.
I was aware of the double action of petty spurge, which is why in my view it should be more effective. However, the Peplin research team are not making any great claims for it. Here is a reply I received from the leader of the research team:
Thanks for you interest. The Ramsey study was mainly superficial BCC (see Table legend and text) (also ref 13), with only 57% CCR; penetration issues may limit effectiveness. The drug is now sold as Picato and licensed for use on actinic keratoses, not BCCs or SCCs.
All the bets Andreas
Andreas Suhrbier | Group Leader
QIMR Berghofer Medical Research Institute
I was aware of the double action of Ingenol Mebutate, and for this reason, I suspect that it is more potent against cancer cells than the extract of eggplant/devil’s apple used in Curaderm. The promoters of Curaderm claim 100% success rate, providing patients apply the cream twice daily for 12 weeks and put up with a good amount of discomfort. In the case of the petty spurge trials, according to one of the patients only a very small amount of the sap was used for three consecutive days, and then for recalcitrant cases, the same one month later. According to another post, Picato is really more dilute than the sap. So, I suspect anything like the same doses of petty spurge sap would work on nodular BCC.
I have access to a plentiful supply of healthy petty spurge, and put three good doses of the sap on the BCC (not my nose, as I wrote in previous post). The result was a horrible looking weeping sore on the fourth day, and is now a large scar. I also have a small scar from one of the band-aids I used to cover it, since I am prone to rashes from the adhesives in these. For this reason, and the conclusion I have come to about the relative potencies of the two treatments, that I have decided not to even try Curaderm. I could not cover the treated area as required.
So, at present I have this ugly scab, plus the smaller scab, which are uncovered. The positive about this is that I can’t feel the lumps that used to be there. I know that these lumps are not the problem. It is the roots being put down underneath that are the real problem and that the sap is unable to get to. However, I suspect that if not all, then most of the cancer cells will be knocked out by this treatment, and there will be less to cut out if I have an operation. However, unless MOHS is used and tests are done to see how many cancer cells there are, which I don’t think is the plan, the fact that there are less cancer cells won’t affect how much the surgeon will cut out. So I am still unsure whether to go ahead with or cancel the proposed operation, perhaps annoying the surgeon (a plastic surgeon) and my doctor.
I have been examining other topical treatments. None of the available approved topical treatments looks as promising as petty spurge. I have read about Imiquimod, and it is clearly slower acting, more painful and prone to had side effects, only treats superficial lesions, and so has no advantages and is very much inferior to petty spurge.
There are other things that are promising, but not properly developed. In Western Australia in 2000, a research team found that tea-tree oil got rid of tumours on the backs of mice. It was combined with another chemical that got it to its target, which is the important thing. I tried using this, along with extra virgin olive oil, crushed garlic and curcumin, all of which have been shown to destroy cancer cells in petri dishes, in the few weeks between getting the results of the biopsy and seeing the surgeon. This concoction might have reduced the length of the BCC from 10 to 9mm, and made the nodules smaller, but I am not sure of this and I think the problem is getting the effective chemicals to the right place. If this could be done, the effective ingredient of olive oil which has been found to kill cancer cells in 30 minutes might be effective, but I don’t know how to get the oil through my skin, and I don’t know whether the chemical is in sufficient concentrations. I have read posts on the efficacy of olive oil, but so far as I can see there is not enough good evidence that it can work, and in the one case where it appeared to work, I suspect it was because the cancer had created an open wound, allowing the good oil to penetrate.
I am a bit annoyed that doctors have not done more research on these potential treatments and what is involved in getting the chemicals to the proper place, since skin cancers should provide an ideal place to study cancer, being more accessible than anywhere else. I think it odd that there has not been a follow up on the tea-tree oil. I suppose the medical profession have made some important advances in the treatment of cancer, but I suspect research is being held up by the bureucratisation of medical research.
So, I am still trying to make up my mind what to do. Agare
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BobCA
43 Posts |
Posted - 09/06/2015 : 20:30:04
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Hi Agare,
There are two things in play here: One is the homeopathic use that has been in use for a long time and the usage has been passed on via word of mouth, the second is the tested clinical use substantiated with data. I have read on this forum that people have used PS for many things in many different ways. Not everything is how Picato is recommended. For example, covering of PS is not recommended while covering of Curaderm is.
What I like to do is use it based on the clinical evidence. Clinical evidence shows that for treatment of BCC it had a 57% effectiveness but on AKs it was much much higher so it is approved for AKs. Now the same cells structure is found on BCC and SCCs and we know it works on these cancers but well does it work, how deep can it go? I still contend that your doctor and surgeon are just being extra cautious because of the 57% effective rate and because yours is deeper than superficial. You might have used it and you might have got all the cancer. If you had that strong a reaction you probably did but what if you didn't? Could it come back, will it metastasize? Since it is BCC unlikely it would metastasize but it could come back.
My recommendation, and I'm not a doctor, is to inform your doctor what you have done so far and see if he wants to proceed or wait and see. If you used PS it will be healed in a week or 10 days. It might make it more difficult for the surgeon because he may not know where the main lesion was. I'm sure he doing MOHs as it is on your face. He could perform another biopsy to see what he finds? I've gone that route with my dermatologist but only with AKs. If I have a biopsy and it is either SCC or BCC I have had it cut out. Although is is now using light therapy with 98% cure rates.
I still think its best if you come clean with your derm and discuss options, risks, and concerns.
Best, Bob |
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agare
17 Posts |
Posted - 09/07/2015 : 04:26:21
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Hi Bob,
That sounds like good advice, which I will follow. Thanks. I will post the final results in case others are interested. Agare
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agare
17 Posts |
Posted - 10/01/2015 : 05:19:16
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Hi Bob,
Just to update you and anyone else on my experiences. The scabs formed from my first PS treatment dropped off surprisingly quickly, in less than a week, and I found the nodules were still there. This, along with careful reading of people’s experiences, not receiving a reply to my email to mrosen suggesting that nodular BC is resistant to treatment and reading what sounded like a horror story from Marsha attempting to treat her nose and eventually giving up on PS, and then visiting another doctor who confirmed the high regard with which the surgeon was held, led me to conclude that I had better go ahead with the operation, despite finding that overall it was going to cost me about $4000. However, I decided that I had time to put in another round of treatment with PS to ensure that cancer cells around the nodules would be minimized, reducing the margin required. I applied some heavy doses. With the last dose I broke off a major branch of a plant to get as much sap as I could, and then for good measure, broke of another major branch and applied this as well. The result was a painful face. With some help, the scabs were off in time for the operation five days later, although a bit inflamed. When I went to the hospital and was ready to be wheeled into the operating theatre the surgeon took one look at me and cancelled the operation for a week until the inflammation has subsided. I stopped using the sap, and to my surprise the nodules were only very slightly smaller. The top one, from which a biopsy had been taken, was clearly smaller, but the bottom one seemed the same size. To avoid self-deception I carefully measured the length of the overall raised area containing the two nodules. I think from when I started applying stuff to it (before I started using PS, to just before the operation it was reduced from 10mm to 8mm. A week later I had the operation, which included using a flap to cover the incision. It was not a a MOHS operation, and the surgeon said there would be a 5% chance of a recurrence. Attending his surgery today, a week after the operation, he said the study of what had been cut out (18mm x 17mm x 6mm deep) showed that there were no cancer cells left, but they were within 0.2mm from the bottom of what had been taken out. The sides were all clear, so it is likely the PS did its job here. Because of the 0.2mm clearance the surgeon estimated the likelihood of a recurrence at 12%. He had cut right down to the muscle, so if there is a recurrence it will come from the muscle. I think this could make things difficult, and I suspect that it is when the cancer gets into muscle or cartilage, or worse, into bone, that it is a huge problem. I suspect this is why Marsha had so much difficulty with her nose, and why PS applied day after day, following SoFl’s advice, just produced a big sore. I think it must be in her cartilage, and she was damaging as many good cells and cancer cells, perhaps more with the PS sap.
In the meantime I have done a great deal of research. I think SoFi’s case, and others, indicates that PS will work with all superficial skin cancers (apart from Melanoma, which is never superficial anyway). You could follow SoFi’s advice, but just applying the sap for three days, letting the scab form and drop off, then doing this once or twice again for good measure, should work. I would follow up because a resurgence means that the cancer cells have been active under the skin and spreading, and this is why a recurrence can be worse than the original, so best not to take chances. The most problematic BCs are morpheoic, since these are the most invasive. I think PC might also work with these, and SoFl’s approach might be more reliable. Where it is really difficult is where it is nodular or cystic, or both, and perhaps all cystic BCs are really nodular. Here the cells have defended themselves against the BC sap. And if this is above a morpheoic development, that is invasive, which I gather mine was, and it is in a sensitive place such as the naso-labial area, or near an eye or on one’s nose, cutting it out might be the best option, although I still think it is a good idea to use PS first to kill surrounding cancer cells. Unfortunately, surgeons are unlikely to take a smaller margin because of what has been done.
Elsewhere, on one’s limbs or trunk, there is room for experimentation. Marsha was a surprising case. I think if one followed SoFi’s advice and used PS like Curederm, continually applying it along with some moisturizing cream (I used tea-tree oil cream towards the end of my treatment on the assumption that this would get more of the PS through my skin, and the tea-tree oil has also been shown to kill cancer cells and could give the PS sap some help) and covering it with something – best micropore tape, then even an invasive cystic nodular BC would eventually succumb, although in some cases, like mine and unlike SoFl’s, it might involve enduring some pain. One could experiment by adding DMSO (dimethyl sulfoxide) gel to get more PS through the skin. I would try this, although I would expect it to be more painful. Where one’s face anywhere near one’s eyes or nose or mouth, is concerned, things are a bit different. I thought Curederm might work if one could put up with using it for up to 12 weeks or more, but this did not work for Marsha which is one reason why I did not try it.
I don’t intend to count on my luck and hope that I am not one of the 12% who has a recurrence. I will treat the area to reduce the likelihood of a recurrence, and have been doing an enormous amount of research. What I look for is people’s accounts of their own experience and also scientific papers where there are any. I am still interested in tea-tree oil and emailed the lead experimenter. She said they did not go beyond the early stages using mice with cancers on their backs because of funding issues and problems with intellectual property rights. She clarified what had been applied. It was a solution of 10% tea tree oil with 90% DMSO. They did reduce tumours together, but neither did when used in isolation. The DMSO would get the active chemicals to the site, and from what I have read, would be far gentler than petty spurge sap or Curaderm (or Sunspot or aubergine soaked in apple cider vinegar, which involves the same chemical), which is gentler than PS from what I have read. I think this is really worth experimenting with. However, I also came across good evidence, including a scientific paper, that showed frankincense oil applied several times a day for a long period – four months or more, can cure skin cancers, without redness, swelling, erupting sores or whatever, and this is what I will use. As a volatile oil I assume this would have very good penetration, although it clearly works far more slowly than PS, or even Curaderm. It requires patience. Putting on olive oil (early harvest extra virgin oil, just in case this also works on skin cancer cells as it does with other cancer cells – colon and breast cancer cells for instance, would be a good choice) and can get through the skin with the help of the frankincense oil. Alternatively, I might use my tea-tree oil (5%) cream.
I could go on for a long time, pointing to what I concluded were dead-ends, but won’t. I think thyme oil also works, but from what I have read, not as well as frankincense. Baking soda mixed with coconut oil works on the surface, but does not penetrate and so tends to result in recurrences. It might be good to start with and then go on to something more aggressive and painful. It is interesting that SoFl, the success story with PS, was writing on another website before this one about using aubergine, and clearly found PS much more effective. I think this is worth knowing. Ginger and garlic might work, but there is no convincing evidence that just putting them on your skin is going to cure you. Other treatments I have found unconvincing. Orange oil, for instance, might kill cancer cells because it kills all cells, but it is also mildly carcinogenic. The same with vinegar. Apart from being curious about the potential of the right kind of olive oil with DMSO or some other means of getting it through the skin, I have not been convinced by any other proposed remedy. Agare.
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BobCA
43 Posts |
Posted - 10/01/2015 : 09:27:39
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Agare, thanks for the detailed post and glad to hear you are doing well. I find it very interesting the the PS didn't get all the cancer.
A couple of questions:
Did your doctors tell you that BCC can metastasize in muscle or did you deduce that yourself? Since muscle cells don't undergo mitosis as rapidly as say bone marrow I would be surprised if an offshoot of your lesion would start a new tumor in a muscle.
I am surprised your surgeon did not use MOHS technique given the location of the lesion. Where do you live? If the surgeon had used MOHS he would have only taken as much tissue as required so you pre-treatment with PS would have save you some margin skin.
All in all it sounds like you did the right thing. Treating AKs and superficial SCC and BCC sounds doable but any cancer that had gone deeper should be treated professionally. Not worth the risk until we know more. |
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Petty Spurge Herb sap for skin cancers
