| T O P I C R E V I E W |
| dan |
Posted - 04/02/2007 : 22:47:18
A new study (April 1, 2007) in Cancer Research http://cancerres.aacrjournals.org/cgi/rapidpdf/0008-5472.CAN-06-3798v1.pdf on mice showed males are much more likely to incur skin cancers due to biological and not behavioral differences. In other words, don't blame the higher skin cancer incidence rate for male mice on worse "sun safety" compliance.
The study found male mice developed tumors significantly earlier than the female mice. Male mice developed significantly more tumors than female mice and tended to have larger tumors. Moreover, the total tumor burden in males was nearly twice that in females. In addition to having more tumors and larger tumors, males had tumors of a higher histologic grade than females, suggesting accelerated progression of the tumors. Thus, when receiving identical UVB exposure, male mice have enhanced skin tumor susceptibility. |
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