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 Zinc sulphate Topical treatment
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Ric

6 Posts

Posted - 06/22/2017 :  08:36:58  Show Profile  Reply with Quote
http://dx.doi.org/10.1016/j.jssdds.2012.06.002
Comparative study of topical treatments versus surgery.Shows use of zinc sulphate at from 2% to 25% solution to cure BCC.Zinc sulphate is used also to cure toe fungal infections.PDF download at top of page.
Ric

Edited by - Ric on 06/22/2017 08:41:36

Ric

6 Posts

Posted - 06/23/2017 :  08:55:06  Show Profile  Reply with Quote
Amazon sells zinc sulphate cream.You can make your own 5% solution by adding 5grams of Zinc sulphate crystals to 95ml of distilled water.

Edited by - Ric on 06/23/2017 08:55:40
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anivoc

645 Posts

Posted - 06/23/2017 :  11:18:48  Show Profile  Reply with Quote
Good stuff Ric.... Thanks for sharing this and your other post on the Mandrake / Mayapple..

years of coming here and I don't believe wither approach has been discussed...Below is the copy and paste from the link above RE Zinc Sulphate

3.2.1. Zinc sulfate
Zinc is one of essential trace elements and zinc sulfate has been used in many medical conditions especially skin diseases as a topical or systemic oral drug; it is used topically in treatment of severe herpes simplex infection, plane warts, melasma, superficial fungal infection and provides antioxidant photo protection for the skin. Intralesional zinc sulfate is found to be an effective therapy for cutaneous leishmaniasis, BCC, xeroderma pigmentosa (XP) and in treatment of viral warts (Sharquie et al., 2005; Punjabi et al., 2007; Heller, 1996; Sharquie and Al-Azzawi, 1996; Sharquie et al., 2007; Sharquie et al., 2008).
Through an open-label case interventional work performed in 2003, intralesional 2% zinc sulfate solution has been used in the treatment of BCC (Sharquie et al., 2005).
Eleven patients (10 males and one female) with BCC were included in this study; they had 100 lesion/s ranging from 1 to 46 per patient (one of the patients had Gorlin’s syndrome) (13.72 ± 9.18) median of 2. Their ages ranged from 46 to 70 (61.18 ± 9.60) years, while the duration of the disease was between 7 months and 36 years (11 ± 11.35 ± 8.49) (median: 2). A total of 100 lesions of BCC, (48 [48%] nodular, 45 [45%] superficial pigmented, 6 [6%] noduloulcerative and 1 [1%] cystic) were infiltrated with zinc sulfate solution mixed up with 2% xylocain. The sites of lesions were 43 (43%) on the scalp, 34 (34%) face, 21 (21%) cheek and 2 (2%) on the chest. The number of injections for each lesion ranged from 1 to 4 (2.06 ± 0.9661) injections. All lesions showed clinical cure: 18 (18%) lesions after first injection, 52 (52%) lesions after second injection, 29 (29%) lesion after third injection, and one (1%) lesion after fourth injection. Local redness, swelling, and tenderness were observed in all lesions. After 2–3 days local necrosis with black eschar appeared in all treated lesions that stayed for 10–14 days and then fell down leaving atrophic scar. This scar gradually disappeared over time leaving a good cosmetic appearance at the end of 8 months follow up. No patient complained of any systemic side effects. Follow up for 8 months showed no residual malignant cells which proved by histopathological examination. The mechanism of action cannot be speculated, although it has been reported that zinc sulfate has local cytotoxic effects. Similarly, zinc sulfate cause local necrosis in the treatment of verruca vulgaris and cutaneous leishmaniasis through intralesional injection. So the mode of action of local injection is mainly through necrosis of lesional tissue. In comparison with other modes of injections like bleomycin and interferon alfa-2b, these drugs are associated with systemic side effects like flu like illness as with interferon alfa-2b also they take long duration to achieve healing of lesion in comparison with intralesional 2% zinc sulfate solution.
In further work, topical 15–35% zinc sulfate solution was used twice daily in treatment of hundreds of BCC lesions and showed very high successful rate. Also, topical 15–35% zinc sulfate solution was applied on lesions in patients with XP and gave very encouraging therapeutic and prophylactic results (Sharquie et al., 2007; Sharquie et al., 2008; Sharquie et al., in press-c; Sharquie et al., 2009; World Health Organization, 2001; Al-Hamdi et al., 2007; Sharquie et al., 2006; Sharquie et al., 2008).
Zinc sulfate solution whether through topical or intralesional way is indicated for treatment of multiple lesions, in patients that are genetically prone to malignancies like XP, epidermodysplasia verruciformis (EDV) and syndromes that are liable for BCC to malignancies or in patients with surgery phobia (Sharquie et al., 2007; Sharquie et al., 2008; Sharquie et al., in press-c; Sharquie et al., 2009; World Health Organization, 2001; Al-Hamdi et al., 2007; Sharquie et al., 2006; Sharquie et al., 2008).
Most recently zinc sulfate solution 25% was reported as an effective topical therapy in the treatment of actinic keratosis (Sharquie et al., 2012).
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anivoc

645 Posts

Posted - 08/27/2017 :  09:26:14  Show Profile  Reply with Quote
Image below is two types I purchased one being the wrong chemistry the other what was used in the study...Brands wise I have no idea which ones are "better"



Well.............


After a week of applying a solution using a certain type of Zinc Sulphate (I'll post details below) to both small and huge lesions I have been dealing with FOR YEARS you can call me VERY VERY Hopeful....

All my tumors are shrinking! Some pesky little ones that I had thrown almost everything discussed on this forum at over several years are shrinking away to nothing!....Again as I have fallen into the "Hopium" trance in the past I will wait and watch over the next month and keep reporting ...

My mix stings a little...or a lot dependent on the lesion, where it is and if it is an open sore or a just a bump....

When I say stings a lot...not to the extent of Zinc Chloride Paste / Bloodroot paste but definitely has me barking for a around 20 to 30 minutes then settles down...I have tried more painful solutions with less success...That beyond a shadow of a doubt they ALL are shrinking tells me I am on to something here ...definitely the "softer gentler way" when compared to the the gold standard of alternative skin cancer treatment Zinc Chloride / Bloodroot paste...

Still not totally painless but at least in my case applying daily on 5 very large nodular BCC's dozens of smaller ones...a lot of AK damage.... Zinc Sulphate heptahydrate, Hi-LR is knocking things out...I've waited a week to post because I needed to be sure.

There is one small lesion I have been keeping at bay for about 7 years with a litany of topicals...orange oil, watered down Zinc chloride, Vitamin C, salacylic acid, Frankincense, Petty spurge, iodine...you name it, the list goes on and on...it persisted. It was so dang small ( Unlike other ones I have ) just to the right side of my right eye at the bottom of my eyebrow... at it's biggest mabe almost a 1/4" wide and 1/8" tall...If I pressed on it it would hurt like there was a shard of glass underneath my skin..

7 days of applying this new solution and it is almost completely gone. I have to press REALLY hard to feel any pain where it is now..I believe in a few more days it will be history...

I always say "Take Pictures" and because I have taken so many "Before" pictures only to not need to take "After" pictures because whatever I was trying didn't work, I didn't take "Before" pictures this time... IT's OK my lesions are huge and gross and this is going to be a long process so I will take some "Before" pictures in the next few days...as this is proceeding I suspect it will be a good 6 months maybe more to make these go bye bye...maybe it won't work completely on the big ones but FOR SURE they are getting smaller / eaten away...It's the little one on the side of my eye that is giving me so much hope...I just couldn't kill it and it appears the battle is almost won....

OK what am I using..
First be aware there multiple types of Zinc Sulphate and I purchased the wrong one the first time I bought ZnSO4 H2O the first time...The study used Zinc Sulphate heptahydrate which is ZnSO4 "7"H2O I'll call it ZSH

I mixed up a 33% solution. Using a teaspoon as my measuring device.
1 "Level" teaspoon of the ZSH / 2 level teaspoons of distilled water...mixed it up and poured it into a plastic dropper bottle.

using the same type dropper bottle... I go to the dollar store and use eye drop bottles...The tops pop off , I dump the eye solution and ut in whatever I am trying...I use a small tile to measure out the drops currently 15 drops of ZPH /15 drops of DMSO ...I use a small makeup brush ( also bought at the dollar store in a set of 3 ) to apply the solution to the lesions...I let thesolution soak in for a few minutes and then on the big nasty ones that are open sores or just big and ugly I apply a thin coat of mt bee's wax / olive oil healing salve ( 5 to 1 ratio) 5 parts olive oil 1 part bees wax in a microwavable cup...nuke for a minute or so...let cool ...you have my healing salve....I add a few drops of orange oil to give it a citrus smell... I then cover the lesions with Micropore tape to keep them clean and out of the view of the public... On the little ones that are not open sores I just leave them wide open maybe apply some Lubriderm on my face 15 minutes or so later....

I started with a mix of 33% ZSH and using dmso I went 2 zph to 1 dmso and applied.....Ouch! I have been slowly lowering the ratio of ZPH to get to a pain level I can tolerate.... right now at 50/50 and I might go lower...The stuff seems to work at the lower levels and not hurt quite as much...

Please keep in mind this is experimental and I am the guinea pig here....If you so chose to try this you do so at your own risk ...do your own due diligence BEFORE You try it...

If you decide to give this approach a try, I'd recommend first trying a small application on healthy skin to make sure you don't have an allergic reaction...Then if all is good , try on a single lesion and see how it feels....so you know kind of what you are getting into...If you can handle that carry on and God be with you.


I'll post pictures here when the change is significant enough to post them... wish me luck and pray for a complete healing!

Tom

Edited by - anivoc on 10/03/2017 10:07:17
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Eddie_T

USA
17 Posts

Posted - 08/29/2017 :  13:12:17  Show Profile  Reply with Quote
Sounds promising, what is the best source for a quantity that fits our needs?
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waverider

76 Posts

Posted - 09/04/2017 :  18:47:47  Show Profile  Reply with Quote
I'm also looking forward to updates on this. We can always use another weapon in the armament to treat BCC. Some things work for some people but not for others -- or they work in one occurrence of BCC but not another occurrence in the same person. The option to hit it with a variety of therapies is therefore very valuable.
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Bonders

USA
4 Posts

Posted - 09/07/2017 :  06:47:42  Show Profile  Reply with Quote
Hey Anivoc, Tom ... Bonder here and I had a bad re-occurance...


Could a person use a cream like on Amazon ...

Zinc Sulfate Topical Cream 4 oz
Kirkman Labs

Does DMSO (Have) to be used ?

I saw this only so far

It was said ...

"OK what am I using..
First be aware there multiple types of Zinc Sulphate and I purchased the wrong one the first time I bought ZnSO4 H2O the first time..

The study used Z "7" H2O I'll call it ZSH

I mixed up a 33% solution. Using a teaspoon as my measuring device.
1 "Level" teaspoon of the ZSH / 2 level teaspoons of distilled water...mixed it up and poured it into a plastic dropper bottle.

Zinc Sulphate heptahydrate which is ZnSO4-7H2O



SO, DO I LOOK FOR ZnSO4-7H2O IN POWDER OR CRYSTAL FORM OR PERHAPS

SOMETHING ELSE?


I TRULY DO NOT WANT TO GO HAVE MY FACE CUT UP FOR THIS BUT, HAVE RUN OUT OF SOLUTIONS.


IS THIS A MUCH (QUICKER AND SAFER) PROCESS THAN THE BLACK SALVE ??

ANY PICS YET ???

REGARDS,

BONDER






Edited by - Bonders on 09/11/2017 10:02:58
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anivoc

645 Posts

Posted - 09/21/2017 :  21:22:43  Show Profile  Reply with Quote
Hey Bonder

Sorry for the late reply and sorry you are having some issues..

I wish I could yell "Eureka!" on this but I can't...It is definitely doing "something" but it is a bit painful each application ( which is daily ) on the lesions that are open wounds...Not so bad on the bumps and it is slowing shrinking things down in some cases but in all much slower than I originally thought or hoped...some seem barely effected while others are getting eaten away...don't really understand why....

Bottom line the jury's out on if it works... I am thinking of making a 50/50 paste with it and flour using DMSO as the liquifier and applying like bloodroot paste on a few smaller lesions and see what happens. I'll update after I try it...

Bottom line for now...Blood root paste is the best but painful solution...Mine have gotten really big to where I am very close to succumbing to the damn knife...fingers crossed and putting it in Gods hands I trudge on...

Edited by - anivoc on 09/21/2017 21:25:08
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anivoc

645 Posts

Posted - 09/21/2017 :  22:19:46  Show Profile  Reply with Quote
Bonder

I checked out the cream on Amazon..read reviews and it looks like that cream is good at knocking out plantars warts and also AK's and eczema...will it work on basal cell tumors...don't know but it definitely appears to work on the aforementioned based on the reviews...a few negative reviews complained it gave them a rash ...

You asked: "SO, DO I LOOK FOR ZnSO4-7H2O IN POWDER OR CRYSTAL FORM OR PERHAPS SOMETHING ELSE?"

It shouldn't matter powder or crystal as long as it's pureZnSO4-7H2O..

In regards to DMSO..... I just went a week NOT using it and feel it was not as effective as when I used it with DMSO

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Bonders

USA
4 Posts

Posted - 09/22/2017 :  10:43:34  Show Profile  Reply with Quote
Hiya anivoc...

Yeah, this is very disappointing for me especially after having www.canceramerican.com hacked so that if you go there, it gets automatically forwarded to God knows where...

I finally gave up and pointed the domain to a picture of my tumor and listed the old site as a (history page) just too tired of trying to fix it but there is a contact form there if someone wants to leave me an anonymous message or something.


You seemed so excited here about the ZPH theory. :(

So, are we back to bloodroot from nature being the actual helping agent rather than the zinc that was so often put in the poultices??


So, the 50/50 solution ...

Does this now mean like one teaspoon of ZPH and one teaspoon of flour with just a snitch of DMSO mixed together in a bottle and then combed onto the area?

or, does one first need to put the ZPH in a mixture with distilled water?

Also ...

Here's a thought anivoc, I am wondering if including orange oil to your remedy might possibly ruin the equation being as though we know it has cancer-fighting abilities on its own ?

One thing I remember from high school science class was to keep items pure as possible when trying to decide on a conclusion from an experiment.

Personally, I have put just straight DMSO onto my face to measure the pain factor and it was doable.

I wonder if just a 50/50 solution of straight ZPH and DMSO onto the wound is a way to go ?

Once Before, you seemed a fan of beeswax included in the recipe :)


AMAZON CREAM ...

https://www.amazon.com/s/ref=nb_sb_noss_1?url=search-alias%3Daps&field-keywords=zinc+sulphate+cream&rh=i%3Aaps%2Ck%3Azinc+sulphate+cream


I keep remembering this about coconut milk and I wonder if this cheap liquid should be used for the apoptosis ...

Consider using this information at your own risk.
Coconut oil is a terrific candidate for topical skin cancer treatments. Coconut oil has a variety of saturated fats, several of which have been determined to have anticancer benefits. Coconut oil is about 50% lauric acid (found abundantly in human milk) that enhances the performance of tumor necrosis (killing) factor present in the body by 60 times



https://sortedbylocations.blogspot.com/2011/12/skin-cancer-home-remedy-that-works.html


Be Well Always,

Bonder

11:02 a.m. 9/22/2017






quote:
Originally posted by anivoc

Bonder

I checked out the cream on Amazon..read reviews and it looks like that cream is good at knocking out plantars warts and also AK's and eczema...will it work on basal cell tumors...don't know but it definitely appears to work on the aforementioned based on the reviews...a few negative reviews complained it gave them a rash ...

You asked: "SO, DO I LOOK FOR ZnSO4-7H2O IN POWDER OR CRYSTAL FORM OR PERHAPS SOMETHING ELSE?"

It shouldn't matter powder or crystal as long as it's pureZnSO4-7H2O..

In regards to DMSO..... I just went a week NOT using it and feel it was not as effective as when I used it with DMSO




Edited by - Bonders on 09/22/2017 11:02:29
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anivoc

645 Posts

Posted - 09/24/2017 :  14:54:29  Show Profile  Reply with Quote
Hi Bonder

I only use my Beeswax salve as a antibacterial healing ointment. It, as I make it will have zero effect on a skin cancer...I apply it after I apply the solution now if I added ZPH or Zinc Chloride to it it probably would be damn effective depending on the ratio...

Remember that though both are Zinc Products...Zinc Chloride is much different than ZnSO4-7H2O two different animals...

Agreed about the science class theory of keep it as pure as possible so you can understand what is the active ingredient....


Just a side note...I was trying some stuff called Gumby Gumby that comes from Australia internally...one of our members here felt it might be the be all end all solution to knocking out skin cancer internally...I have come to believe he is incorrect...Probably not a bad thing to take to help stimulate the immune system but for sure IT IS NOT going to knock out big skin cancers the likes of mine :(


That said....I sourced the gumby gumby from multiple suppliers and one of them happens to be the guy who brought Petty Spurge to the forefront in the medical world... Petty Spurge is a really good skin cancer tool and he shared some incredible stories with me...On the side I have been searching out PS plants and did knock out a fast growing little tumor ( very little @ 1/8" ) very fast when the other things like the ZnSO4-7H2O were not getting the job done on it like I had hoped...

Unlike just using the sap he sometimes would just chop up the PS plant and make a poultice with it...apply to the lesion and watch out....That little one was knocked out with a poultice ...I mixed it in with some wheat flour and dmso and two applications it was gone....

I have some PS growing and have some plants that I am watching at the local park...In about two weeks I'm going to harvest and make a large batch and start trying the poultice on larger ones that I can't seem to get to go away...I'll start with one at a time and see how it goes....

In the mean time I'll hold em at bay with the current ZnSO4-7H2O method....when I do the PS poultice I'll also try the ZnSO4-7H2O poultice... fingers crossed...


Edited by - anivoc on 09/24/2017 15:10:28
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anivoc

645 Posts

Posted - 10/03/2017 :  10:20:16  Show Profile  Reply with Quote
Though this solution does seem to slow down and reverse AK's, for some reason it alone is not completely wiping any basals out. I thought it had completely knocked out a small one but it is still there ...much smaller but now after a month of daily application still not gone...frustrating unfortunately the big ones did shrink a bit in the beginning but they seem to have stopped and are just being held at bay...

It has to be the ZnSO4-7H2O that has caused a new and very unpleasant problem that in anything I had used previously never caused such a big issue.......the tumors randomly start bleeding and really tough to get to stop.... Over the years once in a blue moon I might get what I call a "Bleeder" that gave me a little trouble but since using the ZnSO4-7H2O it has become a much bigger problem...based on this at least in the way I am using this I would not recommend anyone else trying this...It can be a real mess...and if you happen to be in a public place (like trapped on a plane for 4 hours) pretty gross and embarrassing...ugh.

As mentioned earlier I will be making a paste with this this week and applying it to a small bcc to see what happens..I'll report back....

With Black Salve bleeding was never an issue of any major amount almost no bleeding just a TON of pain and swelling then a week or so for it to cool down and another week or so for the lesion to fall out....I was hoping the ZnSO4-7H2O solution mentioned above would kill the lesion without the pain and swelling....The stuff is weird...On the bigger nodule BCC's it really only burns a little...where there is ever an open wound though OUCH but only for about 30 minutes then it settles down...

Not sure what the heck will happen with the paste but I'll be finding out soon and report back..........yikes!

Edited by - anivoc on 10/03/2017 10:24:33
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alice123

USA
4 Posts

Posted - 02/13/2018 :  05:51:16  Show Profile  Reply with Quote
It is absolutely true that zinc sulphate cures toenail fungus. You can apply zinc sulphate in an easy way on your affected toenail. However, if you opt for surgery option then you have to pay a lot for this whereas this remedy is quite cheaper than the surgery. And, it does not even have any side effects. So, try this and get rid of fungal infection soon. You can also know more about toenail fungus at: https://www.bestfootcares.com/category/toenail-fungus/
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Disclaimer: The three most common types of skin cancer are basal cell carcinoma, squamous cell carcinoma, and melanoma. While melanoma is the most dangerous type, keep in mind that any cancer and potentially some cancer treatments can cause injury or death. The various views expressed in these public forums should not be considered as medical advice. See your qualified health-care professional for medical attention, advice, diagnosis, and treatments.