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dan
612 Posts |
 Posted - 07/17/2008 : 00:36:40
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Melanoma incidence rates increasing faster for women than men have captured recent news headlines. As usual, the rate increases are being blamed on increasing sun exposure. It could be, but I have to wonder if increased polyunsaturated (especially omega 6) oils in the diet combined with sun exposure isn't a better description for the cause for the rise in incidence. Polyunsaturated fat consumption is a significant known but rarely mentioned skin cancer risk factor. I think women are perhaps more likely than men to eat so called "healthy" polyunsaturated oils over saturated fat. The mechanism for skin cancer is polyunsaturated fats, being less stable than saturated fats, become more easily damaged by UV when incorporated into skin cell structures. What do you think?
Recent Trends in Incidence of Cutaneous Melanoma among US Caucasian Young Adults
Journal of Investigative Dermatology 10 July 2008
http://www.nature.com/jid/journal/vaop/ncurrent/full/jid2008159a.html#bib2
Overall, the age-adjusted annual incidence of melanoma among young men increased from 4.7 cases per 100,000 persons in 1973 to 7.7 per 100,000 in 2004. Among women, age-adjusted annual incidence per 100,000 increased from 5.5 in 1973 to 13.9 in 2004. For men, incidence leveled off between 1980 and 2004. For women, the rate of increase in incidence declined from 1978 to 1987 and stabilized from 1987 to 1992. After 1992, however, incidence began increasing again.
A second earlier study looked at nonmelanoma skin cancer incidence. Incidence of Basal Cell and Squamous Cell Carcinomas in a Population Younger Than 40 Years JAMA. 2005;294:681-690
http://jama.ama-assn.org/cgi/content/abstract/294/6/681
This population-based study demonstrated an increase in the incidence of nonmelanoma skin cancer among young women and men with a disproportionate increase in basal cell carcinoma in young women. |
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Skin cancer incidence increases faster for women
