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Author  Topic    allelhotmail USA 1 Posts Posted - 01/23/2008 :  16:44:04     I'm against type for actinic keretoses (AKs)--I'm an olive-complected brunette female, and the AKs are on my legs from knee to ankle. Shouldn't I see some results the Efudex 5% is starting to work after 5 days of use? I was not given instructions about the cream's application except to use twice daily. Am I allowed to shower daily? Is any leg "prep" such as washing necessary before each application of the cream? How thick a layer of cream is necessary? Any help will be greatly appreciated. JP Berlin 1 Posts Posted - 01/25/2008 :  14:35:04     It should be working. You should make an inquiry to your dr. stereosb 1 Posts Posted - 01/25/2008 :  20:18:04     I used efudex for 4 weeks. I really didn't see a reaction (i.e. redness and itching) until 10 days. After the 10th day, it seemed to develop rapidly overnight.    Topic

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