Skin Cancer Forum

Skin Cancer Forum

All Forums

Welcome to the Skin Cancer Forums at Topicalinfo!

Skin cancer prevention strategies

Exercise + caffeine = less skin cancer

Note: You must be registered in order to post a reply.
To register, click here. Registration is FREE!

Screensize:

UserName:

Password:

Format Mode:

Format:

Message:

* HTML is OFF
* Forum Code is ON

Smilies

[quote][i]Originally posted by dan[/i]
[br]Exercise plus caffeine led to much lower rates of skin cancer in a new study with mice. The combination enhanced programmed cell death, also known as apoptosis. Apoptosis is a way in which cells with badly damaged DNA commit suicide � UVB-damaged cells in this case.

�If apoptosis takes place in a sun-damaged cell, its progress toward cancer will be aborted,� said Allan Conney, director of Rutgers� Cullman Laboratory.

Compared to the UVB-exposed control animals, the caffeine drinkers showed an approximately 95 percent increase in UVB-induced apoptosis, the exercisers showed a 120 percent increase, while the mice that were both drinking and exercising showed a nearly 400 percent increase over   a group that had no access to an exercise wheel and had no caffeine.

http://ur.rutgers.edu/medrel/science/conney.shtml

Earlier research at Rutgers found that both topical caffeine and topical EGCG, compounds found in green tea, inhibit skin cancer.

http://www.pnas.org/cgi/reprint/99/19/12455
[/quote]

Insert an Image File

T O P I C R E V I E W
dan	Posted - 08/04/2007 : 01:24:23 Exercise plus caffeine led to much lower rates of skin cancer in a new study with mice. The combination enhanced programmed cell death, also known as apoptosis. Apoptosis is a way in which cells with badly damaged DNA commit suicide � UVB-damaged cells in this case. �If apoptosis takes place in a sun-damaged cell, its progress toward cancer will be aborted,� said Allan Conney, director of Rutgers� Cullman Laboratory. Compared to the UVB-exposed control animals, the caffeine drinkers showed an approximately 95 percent increase in UVB-induced apoptosis, the exercisers showed a 120 percent increase, while the mice that were both drinking and exercising showed a nearly 400 percent increase over a group that had no access to an exercise wheel and had no caffeine. http://ur.rutgers.edu/medrel/science/conney.shtml Earlier research at Rutgers found that both topical caffeine and topical EGCG, compounds found in green tea, inhibit skin cancer. http://www.pnas.org/cgi/reprint/99/19/12455
3 L A T E S T R E P L I E S (Newest First)
sebastian348	Posted - 04/08/2008 : 02:25:35 I also heard about this study. Too bad that I am not a coffee drinker :-) Well I guess there are many other ways left for me to prevent skin cancer.
sujan20	Posted - 12/04/2007 : 02:29:56 I heard about Aloe Vera cream that skin cancer can be resolved by applying Aloe Vera cream liberally over the affected part three times daily for atleast three months.
dan	Posted - 08/06/2007 : 23:42:52 Well, here is my guess at why exercise and caffeine inhibit skin cancer. I think the common denominator is ammonia. Exercise causes an increase in plasma NH3 (ammonia) concentration. Caffeine prevents ammonia from breaking down into urea. Combine the two and there is extra ammonia, which I think possibly promotes cancer cell apoptosis or cell death. Perhaps this is one reason why topical skin cancer treatments with added ammonia (eg, combined with orange oil or pancreatin enzymes) seem to work better. http://jap.physiology.org/cgi/content/full/85/4/1502 http://www.jbc.org/cgi/reprint/160/1/249.pdf

Skin Cancer Forum

Snitz Forums 2000

Disclaimer: The three most common types of skin cancer are basal cell carcinoma, squamous cell carcinoma, and melanoma. While melanoma is the most dangerous type, keep in mind that any cancer and potentially some cancer treatments can cause injury or death. The various views expressed in these public forums should not be considered as medical advice. See your qualified health-care professional for medical attention, advice, diagnosis, and treatments.