| T O P I C R E V I E W |
| anne |
Posted - 07/31/2007 : 00:03:42
i have cancer all over my arms and chest. It is squamous cell and its very bad. I have had 9 surgeries. This is my third week on efudex and i am so sick and miserable. Does anyone know if this is worth it? Will it be gone after 6 weeks? I feel i can not take much more . I am so depressed. |
| 75 L A T E S T R E P L I E S (Newest First) |
| Eddie_T |
Posted - 03/26/2018 : 09:56:52
The skin cancer on my forehead returned. I had used Effudex until eruption then switched to Curaderm and Micropore until healed. It left a noticeable crater which I now attribute to cancel cells around the perimeter. The return was around the perimeter which seems to confirm this. I applied flourouracil for a couple of weeks then switched to Sunspot ES and Micropore until healed (about three weeks). The crater is less noticeable this time so hopefully I got it all. If it does reappear I'll just repeat the regimen. |
| anivoc |
Posted - 09/04/2017 : 17:56:42
Efudex is not just local it is systemic...How it was discovered that it had an effect on AK's was it used to be used as Chemotherapy drug...people with other more serious cancers were going through Chemo and all of a sudden AK's are popping up inflamed all over the place and then shriveling up and flaking off...this is what made the Pharm companies develop a lower dose cream for topical application....but it does also get "in your system" depending how much you applied it definitely could cause ak's elsewhere to be affected... |
| hives |
Posted - 09/04/2017 : 15:19:34
Hives, fever, puritans and lethargy with efudex. I have used efudex very successfully according to my dermatologist with my treated skin scabbing off in the past. This time I applied efudex to my entire lower leg and upper arm. After 6 days of twice a day treatment I developed fever, lethargy and extreme itchiness all over my body. This is persisting days even after efudex has been stopped. My actinic keratosis on my non-treated leg and arm are swelling and reddening. I have read one report here by Jack Russell of an allergic reaction. Has anyone else had this? |
| hives |
Posted - 09/04/2017 : 14:52:10
quote:
Originally posted by JackRussell
Allergic Reaction !!! - What the heck? I did this 7 years ago; a 30 day twice a day stint that was very successful. Well get this. I start this time with just a little on the bridge of the nose, collar area and back of hands. I got the expected reaction and after 7 days was settling into the experience when the areas treated started to itch significantly. I went on for 14 days but decided to stop because it did not seem right. Well then on the night of day 17 while asleep an esophageal spasm starts to come on. I have had this only once before after exposure to some chemicals. I narrowly avoided it but then on the following 3 days my hands started to swell and itch like H, and I broke out in hives and lumps. By day 21 I was in the emergency room because my lips were starting to swell. I needed 100mg of IV prednisone. I was put on 60 mg per day. After 3 days I immediately started to taper off the meds and now at day 29 I am off. This was a stupid wild ride. How the heck do I do 30 days like text book and then 7 years later have this crazy reaction? Its as though somewhere in between I acquired that genetic condition in which you cannot use Efudex. Go figure. I am still not right as my body tries to find it's center. I feel a few more days and hopefully I'll be back to center. WOW!!!
|
| Eddie_T |
Posted - 08/30/2017 : 12:20:02
quote:
Originally posted by Eddie_T
Since my Curaderm is well past any arbitrary expiry I am going to give Sunspot ES a try. Interestingly Lane Labs was involved in Curaderm way way back when I tried it on an AK unsuccessfully. I had read of it in a Dr. David Williams newsletter. Maybe Lane Labs was mfg it under license and bowed out when the FDA came down on it.
Sorry for the misinformation the Lane Labs product was Skin Answer not CUraderm. Apparently Sunspot ES is the same or a similar product the feds gave Dr. Lane a hard time with Skin Answer. |
| Eddie_T |
Posted - 08/29/2017 : 12:44:59
The ulcer appears to be healed, I hope and pay that it is. Though I was less than scientific it appears that Curaderm is a good followup if Efudex treatment results in an ulcer. Efudex instructions advise not to Apply Efudex to an ulcer as it might get into the bloodstream and cause side effects. |
| Eddie_T |
Posted - 08/12/2017 : 22:23:32
I haven't procured any Sunspot yet as Curaderm seems to be helping. The ulcer is showing signs of granulation an indication of filling in. I will continue my regimen which is to dry the ulcer and apply Curaderm twice daily covering with Micropore tape. I use a small scrap of tape which goes on white but becomes translucent and almost invisible within 15 minutes or so. I'll report back if this regimen works as it might indicate Curaderm as a companion treatment with Efudex in the case of ulceration. |
| Eddie_T |
Posted - 08/06/2017 : 13:20:59
Almost 20 years ago I has a forehead lesion removed by a plastic surgeon. Mohs was not mentioned but he left the site open until pathology results were in. This is the same site that something reappeared on recently. After trying many of the alternatives suggested in these forums I used Efudex to remove it however it ulcerated at one end. It did heal but left a lumpy scar and the lumpy end reopened. Again I applied Efudex and it ulcerated after a couple of days. Since Efudex is not recommended for application to ulcers I tried vinegar/O3 for about a week with little evidence of progress. It would scab and pucker around the perimeter and pus would drive the scab off after a couple of days. I have a bit of Curaderm from back when it was in a little plastic bottle and am applying it and covering with Micropore tape. The edges of the ulcer are keeping clean but there is still a bit of pus.
Since my Curaderm is well past any arbitrary expiry I am going to give Sunspot ES a try. Interestingly Lane Labs was involved in Curaderm way way back when I tried it on an AK unsuccessfully. I had read of it in a Dr. David Williams newsletter. Maybe Lane Labs was mfg it under license and bowed out when the FDA came down on it. Amazon seems to have the best price on Sunspot right now, $26.61.
|
| Eddie_T |
Posted - 04/10/2017 : 22:07:56
After reading the instructions at this website I think I goofed. I hope I don't end up having to repeat the 5 weeks of application:
http://frontrangedermatology.net/wp-content/uploads/2012/12/images_Efudex_Instructions_for_Actinic_Keratoses.pdf |
| NYArtist |
Posted - 09/14/2015 : 06:12:34
Can someone please give me the recipe for home made eggplant/vinegar for skin cancer? Thanks. szukidavis@aol.com/
quote:
Originally posted by anivoc
The way they discovered efudex worked on skin cancer is when they were using it as a chemotherapy drug the people being treated for internal cancers ( who also by chance had known or unkown skin cancers) would light up everywhere there was a skin cancer.
What efudex does in 4 to 5 weeks bloodroot does in 24 hours. My derm was blown away by my bloodroot treatment pictures and agreed that it is exactly the same reaction as aldara or efudex but just much faster.
BTW Efudex can be purchased out of Canada or Mexico online for much less. I bought a tube in Tijuana when I was down there for $10. It can be ordered online at several online stores.
Curaderm, Sunspot both use the glycoalkaloids derived from eggplant and seem to get a similar reaction somewhere in between Efudex and Bloodroot.
I am currently experimenting with eggplant vinegar mixture with fingers crossed results so far. Several here (Mexico, Rocco and FForest) have had success using the kitchen sink approach using combos with success.
|
| JackRussell |
Posted - 06/08/2015 : 04:27:14
I'm with you, its no big deal. I think the issue is that many people have had life too easy and then to do this is unbearable. My skin it sounds is much like yours but with much less sun exposure. I pushed thru 28 days. I had the purple skin, the scabs, cracking and bleeding, the works but it was no big deal. Sure there was discomfort but who cares; its only temporary. My only regret is that I did not do another week. Though my skin still came out great. It is the ultimate rejuvenation. Wish I did not develop this [now] allergic response that totally messes up my immune system because I would love to use it on my arms and a few other places. My face still looks good 8 years later. Of course I wear sun screen now. |
| Cotchin9 |
Posted - 06/06/2015 : 07:00:32
In the weeks leading up to my treatment, I had sleepless nights worrying about the pain and discomfort that was coming my way. A lot of internet posts had me concerned. I'm 45 with years of '70's, '80's and '90's sunscreenless damage on very fair, freckly skin. Well, I'm now on day 20 of a 21 day treatment and it's just not as bad as it's made out to be! The first 14 days were a breeze - I worked the whole time, and after explaining to people what I was up to, it was incredible the amount who said that they had done it themselves. The 3rd week is where it really kicked into gear.
I'm now beetroot red (I'm doing my entire face) with a forehead complete with flaky skin and scabs. My cheeks and nose are an even deeper ugly shade of purple. The creases where my nostrils meet my face are by far the most painful, but seriously, if a burn victim could click their fingers and trade places, they'd feel like they were sipping cocktails under a tropical gazebo! Yes, you won't look great but I'm yet to meet anyone so far who hasn't been full of encouragement. Yes, you'll be itchy. Big deal!
It's just not THAT bad! Trust me!!! You won't regret it... |
| JackRussell |
Posted - 06/01/2015 : 07:16:37
Hi - I thought I would offer a 1 year follow up to my post of March 27, 2014. In that post, I mention an unusual reaction to Effudex in which I had swelling, hives and esophageal spasms. Things for the most part straightened out after a few weeks of my post. Continuing though I had allergic reactions to environmental things such as pollen, etc that I never had. A year out now and I still have this over reaction but now minor. (No asthma or breathing issues, just skin.). It is just so strange how I did Efudex 8 years ago for a month and it went amazingly well with only the expected pain, etc. but no crazy side effect, and then now if I do it I totally mess up my immune system. I have never been able to find anything on this type of reaction and would love it if someone had some information. Thanks |
| ch2013 |
Posted - 04/15/2015 : 12:39:22
Thanks for updating us all. I'm now post-treatment almost a year. A few small spots are looking questionable, but my last checkup with the dermatologist was clean, and I don't have to go back for 12 months this time. Stick with it --- it's worth it! |
| joe866 |
Posted - 04/15/2015 : 12:32:36
I just finished a 14 days treatment of Efudex, twice daily, and I can't tell you how happy I am now that the pain is subsiding. My face, neck is a bright red mass of spots. My doctor says healing should be rapid, and I'm hoping so. I was unable to work for the last week of my treatment because I could not concentrate on my work with the constant pain and itching. I hope this short sacrifice pays off, and I get some positive results from the efudex treatments. |
| April |
Posted - 01/25/2015 : 21:46:38
Is this efudex usually a one time treatment? or does it have to be repeated? Also it appears it effects all the skin area - such as the face and if there is a issue under the skin that it destroys it, to prevent from having mohs, etc. and it also destroys small BCC that may be on top of the skin?
Am going to the Dr next week and think I have one popping up and would like to ask if I could use this cream in that area and see if there is a reaction, because of where it is, if a biopsy is done it may leave a scar on the cheek area.
|
| ch2013 |
Posted - 05/07/2014 : 19:45:32
I did take some time off from public work mainly because of the appearance, and because I was noticeably tired while using Efudex. Also, my skin was very photosensitive, and sunscreen stung too much to apply, so I stayed indoors as much as possible, and wore protective clothing, gloves, hat, and sunglasses when I did go outdoors. I've been keeping a 'blog' with photos of my progress. It's helpful because sometimes I don't think my skin is improving (or worsening) and the photos help me see progress. http://skincancerjournal.blogspot.com/
Good luck with your treatment -- keep us posted when you start over Memorial Day. |
| WolfpackGirl |
Posted - 05/07/2014 : 19:36:47
Hey everyone!
Thank you for your courage and taking the time to post all of your experiences with Efudex treatment.
I'm in my mid-30s and very fair-skinned, and I have had 9 instances of BCC and melanoma, requiring several surgeries (1 Mohs surgery). I have a lot of AK and a small BCC along my hairline and on my cheeks. My doctor suggested that we attack it all now with a 14-day course of Efudex.
When I was in the office recently for an excision, I asked if I should expect to miss any days of work, and the doctor kind of laughed at me. I don't think that this is a crazy question! I drive 50 miles to work each way and I'm concerned about trying to wear sunglasses in the blinding morning sun(my temples will be treated). I'm also worried that I won't be up to working if I'm in pain and I haven't slept very well. Infection is a slight concern given the open sores as well.
I like to think that I'm fairly tough (I've passed several kidney stones!), but I'm definitely concerned that this treatment will be worse than the doctor said. She basically made it sound like mosquito bites or a mild sunburn (as she handed me the brochures with scary pictures of Efudex treatment).
It was hard to try to schedule a block of time for treatment. I will start Efudex over Memorial Day weekend, as I have a big work deadline before that and a family reunion at the end of June that I have to travel to. I will try to post about my experience as I'm able to.
Again, thank you all for the time you've taken to share your thoughts and advice! |
| sunni |
Posted - 05/02/2014 : 01:20:10
Lately I've read on a few derm sites and skin cancer blogs about a new protocol for BCC, efudex applied weekly for 8-9 months. This is supposed to kill cancer without inflammation or burning. How can this work if inflammation means the efudex is working? Has anyone known this protocol to be successful? |
| ch2013 |
Posted - 04/30/2014 : 07:23:04
Thank you! Thank you! |
| peterjm1003 |
Posted - 04/30/2014 : 07:18:59
Hi,
the reactions I can see from the photos indicate superficial or pre-malignant change - in other words they don't look like invasive SCC. Even if invasive that doesn't meant metastatic. So my initial impression is - don't worry.
(Qualifier - see a local doctor or dermatologist to confirm - I live in Australia and not registered to practice in the US)
Reaction to efudix doesn't mean it is confirmed SCC, it just means atypical cell. Metastatic disease is quite rare, 5-10%??? I think someone pulled that number out of their butt. A lot of these lesions will never progress beyond superficial atypia or intra-epidermal (superficial - confined to the epidermis). Primarily be concerned about spots/lesions on the face or neck or rapidly changing lesions.
Just to emphasise - reaction to efudix is NOT a diagnosis of SCC. I would recommend re-treat in 12 months and note any changes.
Thanks for reading |
| ch2013 |
Posted - 04/30/2014 : 06:52:15
Thank you for the info! I do have specific questions you may be able to help with.
If I have one or more active SCCs show up in the course of this treatment, how do I know there aren't more lurking in other areas of my skin? My first round on my forearms and hands uncovered over 70 spots total -- still healing, so don't know yet if the cream killed everything. On day 13 of round two -- this time upper chest and neck, and I'm covered in spots/rash. If spots show up every place I use Effudex, what does that say about all the areas I am not using it?
I'm reading conflicting statements about the risk of SCC metastasizing. Some research says only 5-10% do, other research says more. And does that mean from the total population of diagnosed, or per patient, or the number of lesions or identified SCCs?
Thanks for your input. Attached image.![]()
Image Insert:
32.97 KB |
| peterjm1003 |
Posted - 04/30/2014 : 06:10:25
Just a quick post to see if anyone needs specific advice.
I noticed anivoc has already recommended picato as a much quicker alternative to efudix, with similar effects but over a much shorter time frame.
I would definitely endorse that thinking. It is generally much more expensive, but is based on an extract of petty spurge/Euphorbia peplus - see the posts on that thread.
Efudix (5-Fluorouracil) works by disrupting the cell replication cycle because it is an analogue of one of the base pairs in DNA. For rapidly dividing cells (ie cancers and pre-malignant cells like actinic keratoses), they are preferentially destroyed, but this then involves the body's immune system, causing localised inflammation - sometimes severe. Some people react very strongly and are in a whole world of pain. Efudix works but it can be nasty.
If you are using efudix, the following should be noted :
1. Avoid the sun - it is photosenstive and this reinforces the inflammatory response
2. Use a basic moisturiser if this does not irritate - this will not affect the action of the efudix.
3. Use twice a day initially until a reaction develops then cut back to once a day.
4. Use for 3 - 4 weeks for Actinic keratoses (field treatment), up to 8 weeks (spot treatment) for proven or suspected intraepidermal carcinomas
5. If the reaction gets too bad, stop or cut back to every second day. Consider repeat course after lesions have resolved
Thanks for reading
|
| ch2013 |
Posted - 04/28/2014 : 08:59:04
I finished a round of Efudex on my forearms and hands, and now am 10 days in on my upper chest and neck. My arms and hands still have red spots healing. I posted a blog about this journey will photos, and included some other resources in it too. Hope it's helpful to your journey. http://skincancerjournal.blogspot.com/ |
| Colbres |
Posted - 04/01/2014 : 09:16:29
I have been using Effudex on my lips. I am finished with my treatment but am wondering how I can go out into the world while I heal. I would run if I saw myself; I look contagious and HORRIBLE. Any suggestions? |
| Jans109 |
Posted - 03/28/2014 : 07:57:01
The allergic reaction is really scary! I'm sorry you've had to go thru this and hope you're fully healed soon! I feel so fortunate in being finished with my treatment and just hope I don't have to look at another one in the future. This is forum is such a good outlet to us all! |
| Jans109 |
Posted - 03/28/2014 : 07:53:59
quote:
Originally posted by JackRussell
Allergic Reaction !!! - What the heck? I did this 7 years ago; a 30 day twice a day stint that was very successful. Well get this. I start this time with just a little on the bridge of the nose, collar area and back of hands. I got the expected reaction and after 7 days was settling into the experience when the areas treated started to itch significantly. I went on for 14 days but decided to stop because it did not seem right. Well then on the night of day 17 while asleep an esophageal spasm starts to come on. I have had this only once before after exposure to some chemicals. I narrowly avoided it but then on the following 3 days my hands started to swell and itch like H, and I broke out in hives and lumps. By day 21 I was in the emergency room because my lips were starting to swell. I needed 100mg of IV prednisone. I was put on 60 mg per day. After 3 days I immediately started to taper off the meds and now at day 29 I am off. This was a stupid wild ride. How the heck do I do 30 days like text book and then 7 years later have this crazy reaction? Its as though somewhere in between I acquired that genetic condition in which you cannot use Efudex. Go figure. I am still not right as my body tries to find it's center. I feel a few more days and hopefully I'll be back to center. WOW!!!
|
| JackRussell |
Posted - 03/27/2014 : 16:42:35
Allergic Reaction !!! - What the heck? I did this 7 years ago; a 30 day twice a day stint that was very successful. Well get this. I start this time with just a little on the bridge of the nose, collar area and back of hands. I got the expected reaction and after 7 days was settling into the experience when the areas treated started to itch significantly. I went on for 14 days but decided to stop because it did not seem right. Well then on the night of day 17 while asleep an esophageal spasm starts to come on. I have had this only once before after exposure to some chemicals. I narrowly avoided it but then on the following 3 days my hands started to swell and itch like H, and I broke out in hives and lumps. By day 21 I was in the emergency room because my lips were starting to swell. I needed 100mg of IV prednisone. I was put on 60 mg per day. After 3 days I immediately started to taper off the meds and now at day 29 I am off. This was a stupid wild ride. How the heck do I do 30 days like text book and then 7 years later have this crazy reaction? Its as though somewhere in between I acquired that genetic condition in which you cannot use Efudex. Go figure. I am still not right as my body tries to find it's center. I feel a few more days and hopefully I'll be back to center. WOW!!! |
| Jans109 |
Posted - 03/24/2014 : 10:40:17
After going thru my initial 2X daily for 2 weeks on my nose and cheeks, I finally had my dermatologist visit. He said all pre-cancerous spots were taken care of but he still had to freeze a place on my nose. In addition he froze 10 spots on my forehead. They are all almost healed now. (my appt. was March 6th) I was surprised he didn't have me do the Efudex on my forehead, but I would by far rather have them frozen off if possible. However, most of the area where I had the Efudex treatment now looks great! So overall, I'm pleased. |
| rick789 |
Posted - 03/23/2014 : 05:04:05
Has anybody used Effudex on their lip with success? If so what was the frequency of your application? I was told to use it twice weekly for 3 months, this was some time ago, but I didn't get the problem cleared up. I'm considering alternative options but not sure what yet. Thanks in advance for any advice or opinions. |
| ch2013 |
Posted - 03/18/2014 : 17:00:23
So glad I found this forum! Doctor prescribed Efudex for my hands and forearms, and suggested I do some research first before starting it. Guess she didn't want to tell me about the side effects and pain. I'll keep reading the posts here. |
| Longdrop |
Posted - 02/27/2014 : 17:13:26
I have posted on this site before about my experience with Efudex as a full face treatment and as a targeted treatment. Thought I would add one more! I went to the GP with a red spot on my leg and he referred me to the plastic surgeon who confirmed the BCC and booked me in for surgery ($650). I suggested I try Efudex again and he supported this option but expressed doubt as he felt the BCC was too deep. I tried it anyway, twice a day for three weeks and the spot seemed to reduce. Anyway, six months later, I went in for the surgery and while on the table mentioned the Efudex treatment. The surgeon took a closer look at the blemish and confirmed it was clearing up with no sign of infiltrations and gave me my $650 back. This stuff is seriously good and I recommend anyone try it before surgery or any more invasive treatments - for BCC's at least. Just in passing I should mention I also had a BCC on the other leg some years previously which I ended up with a week of pain, a skin graft and a bill for several thousand dollars - that was the dermatologist who suggested I try Efudex!
And thanks too for this excellent resource, whoever you are who set it up! |
| Jans109 |
Posted - 02/01/2014 : 09:53:15
At day 27 after 14 day 2X daily treatment. Finished treatment and waited for the worse. Other than looking kind of "bad", with redness, peeling and some crusting, plus a bit of itchiness and some pain, I feel I have been really lucky. Of course, my doctor hasn't looked at my face yet. He didn't want to see me again until March! (sound familiar?) So I await his verdict. I started using makeup again a couple days ago and almost feel my normal self, even with a little peeling, etc. I will not be a happy camper if I have to start from scratch! |
| dipendy |
Posted - 02/01/2014 : 06:30:25
Thanks for the help. I am just getting the efudex due to the expense. I also have decided to only great areas I can cover for the safety of my grandchild. This will be day one so anyone with side effect warnings or tips are appreciated. I will also keep my bed and bath locked to prevent my lil one from being around this medicatuon. I have to say I'm scared but seeing everyone on here strength does help much love and thanks to you all |
| mmj |
Posted - 01/20/2014 : 14:47:29
I just finished my Efudex 5 days ago...it is peeling and at night I bleed a bit but it is clearing up I am glad I did it....it wasn't the most fun I have had but the outcome will be worth it....I did the 21 days 2x daily for 1 week and then 1x daily for 2 weeks..................I did get a lot of reaction ...I WILL USE SUNSCREEN it seems to be clearing rather quickly
update.......I have been off efudex 10 days .....and my skin is a little redden in areas but it is healed......I AM VERY glad I went through this...... |
| mmj |
Posted - 01/20/2014 : 14:33:25
quote:
Originally posted by Jans109
Finished 14 day of 2x a day treatment yesterday. Now I wait to see what happens next. Very little discomfort so far. Have spots on bridge of nose and one cheek. No visible reaction on other cheek so far. I feel so fortunate in comparison to others here on this forum, but will continue to report back for those that are receiving the 14 day treatment. Over and out.
|
| Jans109 |
Posted - 01/20/2014 : 04:43:11
Finished 14 day of 2x a day treatment yesterday. Now I wait to see what happens next. Very little discomfort so far. Have spots on bridge of nose and one cheek. No visible reaction on other cheek so far. I feel so fortunate in comparison to others here on this forum, but will continue to report back for those that are receiving the 14 day treatment. Over and out. |
| Jans109 |
Posted - 01/13/2014 : 06:59:56
On my 8th day of treatment and have some red spots now although not much discomfort yet. My main treatment is on my nose. Having rhinitis I use a lot of Kleenex. A couple times I have inadvertently wiped some medication off before it's completely dry. Can someone tell me if I should reapply or not?
Having a hard time trying to figure how to "post" rather than "reply". Duh |
| dipendy |
Posted - 01/13/2014 : 04:44:46
Thank you both for the info. That was the first question I asked my Dr. Is about it being around my grandchild and he said ily would b safe as long as its dry. I wasn't convinced as u said since its so rough on adults. I'm so appreciative for the responses. Best of luck for you all. |
| Jans109 |
Posted - 01/11/2014 : 11:08:13
dipendy,
I believe you are correct in being concerned about a 3 yr old around this stuff. I am only treating my nose and cheek areas and am concerned about touching after applying (before it's dry)and somehow getting it in my eyes or nostrils. I have rhinitis and have a constant runny nose. This is toxic stuff and pretty scary! I am on day 6 and still waiting for reactions. But you're having heavy duty treatment. Good luck!! I hope it all goes well with you. Keep us all informed! |
| anivoc |
Posted - 01/11/2014 : 09:34:27
quote:
Originally posted by dipendy
Hello everyone. I have recently been prescribed efudex cream. I am concerned about using this on arms face chest and neck around my three ur old grand daughter. Does anyone know if it is safe to have on me with her around. Dr says ok as long as its dry but what if I sweat or she licks me (she likes to pretend she's a dog lol) any help would be appreciated.
Hi Dipendy...I moved this into the Efudex forum...
Efudex is VERY powerful stuff with lots of side effects on adults. I would be VERY careful around a child with it... I recommend you going back to your doctor and reminding him that you have a 3 year old...get his recomendation...and also his opinion ( if he has one) on picato gel.
Picato Gel is a new FDA approved cream that is very effective without near the toxicity of Efudex...
Good luck |
| dipendy |
Posted - 01/11/2014 : 08:18:13
Hello everyone. I have recently been prescribed efudex cream. I am concerned about using this on arms face chest and neck around my three ur old grand daughter. Does anyone know if it is safe to have on me with her around. Dr says ok as long as its dry but what if I sweat or she licks me (she likes to pretend she's a dog lol) any help would be appreciated. |
| mmj |
Posted - 01/11/2014 : 03:40:03
also don't stop ....you have to make it up on the end....I am doing 21 days...done next wed.....it burns some and itches but I am told the end results are worth it.....get rid of those nasty cells |
| mmj |
Posted - 01/11/2014 : 03:36:57
well it showed through anyway after a couple hrs.....so today I will just face it...I work in a nursing home and don't want my residents to be upset for me,,,,,,when I first started I thought boy there isn't much here....BUT it it really worked in the middle of my face from forehead to chin and on my chest my Dr said to put on the bridge of my nose ...his nurse said do the whole face as it will not hurt good cells.....glad I did all at once..............I have been a sun lover all my life and I am now 67.....and still go to MX will just use sunscreen here on out
|
| Jans109 |
Posted - 01/10/2014 : 05:05:58
MMJ,
I am on day 5 of my 14 day treatment and so far I've had almost no reaction. Just a little redness in some spots. From what I have researched, I would advise against makeup. I know that's difficult, but I personally don't want to risk any problems that may cause. What reactions have you had? I'm staying inside fearing worse reactions from the sun. I am a 76 yr old woman and only treating the bridge of my nose and cheeks areas. I'm "on hold" waiting to discover what's in store from Efudex! |
| mmj |
Posted - 01/09/2014 : 14:42:37
6 days left I have to work this weekend and I really need to wear foundation............I hope this doesn't mess up the work I have done |
| Jans109 |
Posted - 01/03/2014 : 10:53:38
JackRussell,
Thanks for the reply and advice. I will use your suggestion of patting water on my face. I've also read about cold compresses. I agree that this will be as much psychological as physical. I've come to terms with it and now just want it to be done. And you are right, there are so many other people on this forum with much more severe problems. I am thankful for the small areas I have to treat.. I think one of the reasons my derm. only prescribed the 14 day treatment and on the small area is because I am a VERY senior lady! So he probably thinks I'll kick the bucket before I need more! I might fool him though! :) |
| Jans109 |
Posted - 01/03/2014 : 10:48:23
deruo,
Thanks for the reply! I'm so nervous about starting this treatment, but know I have no choice. I am so fortunate in only being prescribed the 14 day treatment, I hope! I would hate to have to start it all over again. I hope you are right and I won't need the Aquafor at all, but I am sceptical there. I'll keep you posted after I begin treatment. Again, thanks! |
| JackRussell |
Posted - 01/03/2014 : 06:53:21
....also Jans109, I found that patting a little cold water on my face throughout the day offered some relief. Your treatment though, will be as much psychological as physical. Pace yourself. In the end, I found it a healthy exercise in learning to appreciate what some other people have to live with as a permanent condition and to appreciate that I am fortunate. (PS - I had a little flaky skin on the bridge that Effudex cleared up. But now almost 7 years after it has returned. I wish I did 6 instead of 4&1/2 weeks.) |
| deruo |
Posted - 01/02/2014 : 21:07:40
Jans109,
Yes, it is okay to use during treatment, but you should wait at least 2 or 3 hours after applying the Efudex before putting the Aquaphor on.
If you read through all the pages here, you'll get a difference of opinion on it's usage, but I don't think I started using it until week 3. You may not need to use it at all if you're only doing a 14 day treatment. If memory serves, I don't think I saw much of a reaction at all until day 7 or 8.
It really helped loosen up the tightness on my face (I did my entire face and scalp at once), during my 4th week of treatment, and the first few days after treatment finished. The important thing is to not apply it right away as you want the Efudex to sink into the skin to do its thing before applying anything on top of it that may reduce it's effectiveness. Don't put on too much as it can be difficult to wash off later, and your skin will be tender, so you don't want to wash it that vigorously.
Good luck with your treatment! |
| Jans109 |
Posted - 01/02/2014 : 11:46:39
Starting 14 day treatment 2X a day this coming Monday. After researching effects I'm quite concerned. My treatment of Efudex will be on bridge of nose and cheeks. The Dr. said to use Aquafor to ease discomfort. Anyone know if it's ok to use during treatment? |
| Deb333 |
Posted - 10/01/2013 : 21:42:03
Can anyone tell me what I can use for pain when I start efudex cream for my lips? |
| craigeppelstun |
Posted - 09/28/2013 : 21:32:19
I am 44 fair skinned australian builder male and have sun damaged skin.
I am on day 6 and of effedex and at this moment have no effects from the ointment |
| zengrrl |
Posted - 09/27/2013 : 00:44:00
Hello All - in whatever time era you read this,
Thanks for this great forum of users, where we can learn so much more than from our practitioners! I'm Day 8 of 14 days 2x/d for Actinic Keratosis on my nose & a spot on my wrist. While I have 4 small bright red open spots + a reddened background matrix over the rest of my nose, I'm not having pain, only discomfort so far. The derm MD had recently excised a patch on my nose as a containment + biopsy tho, so that part of my nose was brand new skin anyway. It seems like the pain reaction may be related to severity of the skin problem & the amount of surface area involved. Some people here had to treat a lot more area than I'm doing.
In the previous 20 yrs of AK treatment with other derm MDs, my nose was "treated" with Vaseline, retinol, cut, frozen & most recently (before fu5) was Aldara, which made me grow a few "horns" as it reacted with hidden spots. The removals gave about 1-1.5 yrs clean & the Aldara gave me 2+ yrs the first x, but only about 6 mos the second x. So I chose fu5 out of the 3 options the current derm MD gave me - hoping that the bio-chemical approach seemed at least more effective than just removal & I hadn't tried fu5 yet.
Many strong spirits on the site & generous to spend time helping others going through this journey. The variability in regimes is confusing - hopefully rationally related to the specific Needs of the individual situation, but the MDs are not doing enough education with their patients to explain about the spectrum or regime. This site is so helpful to fill in that deficit! |
| Cheeno |
Posted - 07/24/2013 : 08:06:03
I didn't get as strong a reaction to the twice a week over several weeks Efudex treatment as I had hoped for. That's why my doctor tried Picato - I had a very good reaction to Picato and it was much quicker - very red and scabby for 4 - 5 days then cleared up very quickly. It is only for use on a small area at a time.
With the extended Efudex treatment I didn't really flare up badly at all - just some mild redness and at no time did I feel that I couldn't be seen in public. I found it tedious to continue for the extended time - 10 - 12 weeks |
| Matt |
Posted - 07/23/2013 : 02:15:37
quote:
Originally posted by Cheeno
I have used Efudex several times but recently my doctor prescribed a new treatment - Picato. It effectively does in 3 days what Efudex does in 2 weeks. It can only be used on small areas at a time and is pretty new - I think developed in Australia but has been available in USA for several months; available in Australia only for a few months. I am very happy with the results and was only out of action for a week as opposed to several weeks with Efudex
G'day Cheeno,
I have been given the same advise by my Dermatologist as you did in regards to Efudix for treating AK on my forehead, a nine week program of applying it twice a day on Saturday and Sunday only. I think my dermatologist believed I worked a 5 day week when I actually do 21 days on 7 days off!. How did this regime work for you?, did it successfully clear the AK, BCC's?. How bad did your skin flare up?. Sorry for the questions, it's just I'm about to start my 21 day swing in the middle of nowhere and would like to know what to expect. My Derm said very little, didn't say anything about it being a chemo drug and just said I'd get a smaller reaction this way, nothing about how much smaller mind you!.
I've noticed your now going down the Picato route, I am tempted to look into this because I have been advised it is quicker and just as effective..
Matt
|
| drboyd |
Posted - 07/18/2013 : 00:33:54
Sorry to jump in at the tail end (or maybe not) of this thread, but I just finished my last day of efudex (21 days times 1/day) this morning. I plan to tell the doctor that it will be quicker, easier, and less painful to do this next time with a welding torch. 
My face looks roughly like I was dragged behind a cattle truck by my heels - and to make it worse, I've been in a large meeting for two days now (one more day to go) and I'm wearing a baseball cap pulled low over my bright red forehead - so I don't scare the nice  people. And of course, the cap just makes my forehead itch all the more.
Tomorrow morning, I plan to start with some antibiotic ointment and cortisone - hopefully my life will start to be ever-so-slightly less wretched as time passes.
Eeeewwwrf! That's what I say about efudex!
|
| andrewecd |
Posted - 07/16/2013 : 19:38:05
Fiona. Not long to go, good luck. It is well worth the journey in the end. You will get many comments on how great your skin looks when all over. I was told to use the QV cream also. It worked very well. I continue to use it after shaving. |
| FionaKirk |
Posted - 07/16/2013 : 00:03:08
Good Afternoon to fellow Efudix survivors :)). I am now at day 15 it seems forever ago that I started and forever to go to get to day 21. I have thank goodness not turned red to 100% of my face but a good 85%. It is truly amazing to see the size of cancer in my face and the depth it seems to be. I had a fantastic response fairly quickly to the large areas of cancer but only in the last 3 days many smaller ones so maybe they were deeper, I'm not sure? But I do have another appointment at the Cancer Clinique in two days to see if they are going to extent treatment another week... I sooooo hope not! In way of relief the Doctor at the Cancer Clinique told me to wash my face with QV it is a cream and cleanser but has no chemicals perfumes etc. it is an incredible relief does stings a tad at first but gives a little relief before having to apply efudix again. They said to use QV cream once I finish too to help with putting moisture back into the skin as it heals. She also said no matter how tempting it is do not rub or peel skin off, do not rub under water to get it off just let it fall off naturally and you will have less burning and tenderness. Anyway that's just some of my experience.
Oh and a big thank you to Deruo who has been a wonderful help through all of this xoxo |
| jamesd |
Posted - 07/14/2013 : 11:56:02
after cancer is dead try a poltice of flaxseed meal mixed with hotwater to form a paste cover with steril dressing wash and change daily cancer will fall out when ready 7 to 10 days we use a mixture of 10 drops iodine, 10 drops carbolic acid, one quarter teaspoon copper sulfate ground super fine to 3.5 ounce jar vaseline. hardley ever leaves a scar, be careful, getting hard to find good iodine, carbolic acid the best antiseptic ever, almost impossible |
| deruo |
Posted - 07/14/2013 : 11:25:10
quote:
Originally posted by Nutty
Can anyone suggest some cream to help the recovering process? How long should my skin take to get back to normal?
Nutty, I found that anything cream-based hurt too much for the first few days after treatment ended. I only used a product called Aquaphor (which is much like Vaseline or petroleum jelly) for a few days to relieve the tightness. After that, I applied nothing except sunscreen (if I was going outside). You will probably find that the first few days after treatment ends to be the worst as the Efudex continues to do its stuff. Then, the intense redness, flaking and pain subsides quite quickly. You'll probably be amazed at what a difference a week makes. Mind you you'll probably be various shades of pink for several months, and I found that the patchy pink patches would intensify after washing or applying sunscreen/moisturizer to my face, for about an hour or so. I think it was about 4 months before I think my skin was back to normal. Most of my friends thought it was back to normal well before that.
As far as cream to help the recovery process, I don't think that is necessary, though your Dr. may have other ideas, depending how raw and oozing you are by day 30.
Hang in there, those last few days are difficult! |
| Nutty |
Posted - 07/14/2013 : 02:38:13
I have almost finished 4 weeks x twice a day of Efudix treatment.3 days to go! Reading everyone's comments has really helped, I was told very little about the treatment except that the skin had to get very red and sore for the cream to work. I only had a few patches, but the cream has picked up lots of places that I didn't realise I had. I have had to carry on working - I teach, but the kids have been very good, although I haven't given them all the details. My face is very sore now, but I'm looking forward to Wednesday when I can stop. Can anyone suggest some cream to help the recovering process? How long should my skin take to get back to normal? Thanks to everyone who has posted their experiences, it has really helped. |
| deruo |
Posted - 07/12/2013 : 10:31:54
Picato sounds very interesting Cheeno. If you hadn't mentioned it here I never would have spent an hour reading about it this am instead of working! ;-) I'd jump at the chance to do in 3 days what took 21-30 with Efudex. It would seem to be a walk in the park comparibly speaking. I have a followup with my Dr in November for my 6 month check-up so maybe I'll ask her about it.
Fiona, I think anyone that has done a treatment of Efudex is a hero. Believe me there were days where I was ready to give up, especially towards the end. I skipped a treatment and then felt guilty and worried whether skipping that one would mean having to do it all over again. That inspired me to continue. Now that it's a distant memory, I'd only hesitate a little to do it again. |
| Cheeno |
Posted - 07/12/2013 : 06:33:35
I have used Efudex several times but recently my doctor prescribed a new treatment - Picato. It effectively does in 3 days what Efudex does in 2 weeks. It can only be used on small areas at a time and is pretty new - I think developed in Australia but has been available in USA for several months; available in Australia only for a few months. I am very happy with the results and was only out of action for a week as opposed to several weeks with Efudex |
| FionaKirk |
Posted - 07/11/2013 : 21:32:40
Good Afternoon, I think I will call you my hero! You did 30 days? I am at day 11 and very red itchy and sore and can't believe I have 10 days to go. I am thankfully not at work but will be Monday week because my boss is a grump and time off always puts him out. Funny I am at a loss for words, not usual for me - I think being quiet in my mind helps....
Fiona x
|
| deruo |
Posted - 07/11/2013 : 18:48:23
How are you doing FionaKirk? |
| FionaKirk |
Posted - 07/06/2013 : 11:19:10
Thank you so much Deruo for your reply. It's so nice to know someone who has been there and is willing to be around and still answer questions. I wish you were sitting here with me holding my hand as I am quite scared about the whole thing. I will advise everyone not to have teeth extracted the same week you start this, but I guess I wouldn't have done that should I have known the full extent of what Efudix is. I will make sure I keep those codiene on hand then for a few weeks time. Thank you again from Canberra AU |
| deruo |
Posted - 07/06/2013 : 06:48:24
FionaKirk, I seriously doubt that codeine and amoxicillin would have any effect on the Efudex/Efudix reaction. (In fact, the codeine may be handy to have in a few weeks! ;-) I seem to recall that it was about a week to 9 days before I started seeing any real reaction after applying 2x per day. You didn't mention but how many times per day are you applying and for how many weeks? |
| FionaKirk |
Posted - 07/06/2013 : 00:34:22
Hi, I'm hoping there are still people on this forum.
I started my Efudix treatment 6 days ago. I was never told by my Cancer Specialist of the degree of this treatment nor that it was Chemotherapy. So to eliminate time off work I combined having my 4 wisdom teeth extracted on Monday (today is Saturday), I also started Efudix Monday night. I ended up with an infection in one extraction and an ear ache, so have been taking Codeine and amoxicillin. I am wondering if these medications would have stopped the Efudix working correctly as I have had very little reaction at all. Glad for no reaction as I read more and more about it, but also want my BCC's to go already having a 5cm tumor removed from my peck area. I am treating me whole face due to 4 BCC and several precancerous areas. Appreciate any help.
Fi |
| deruo |
Posted - 05/15/2013 : 22:51:16
quote:
Originally posted by Snitz
Here in the UK, they don't tell you anything about what the treatment is going to be like. You get given a leaflet that shows the stages of the treatment, red skin, peeling etc, but no mention of the pain.
This seems to be fairly common in other countries too, Snitz. My Dr. told me I "may experience a little bit of reddening". An understatement if ever I heard one. I didn't even find out it was a topical chemotherapy drug until I got odd looks from the Pharmacist and decided to Google what it was I had just purchased, while in the parking lot sitting in the car.
Drs. need to realize that some patients want to know what to expect, especially when we start looking like napalm burn victims and can't get in to see the Dr. We'd like to know as much as we can beforehand. |
| anivoc |
Posted - 05/15/2013 : 21:55:21
Snitz...funny stuff for a not so funny journey...
Cool that you can joke about it now..
Glad you healed up and thanks for sharing your experience
Tom |
| Snitz |
Posted - 05/14/2013 : 16:24:01
Here in the UK, they don't tell you anything about what the treatment is going to be like. You get given a leaflet that shows the stages of the treatment, red skin, peeling etc, but no mention of the pain.
I did the treatment for 4 weeks and after day two, it started to burn. By day 7, I was in agony. I didn't bother with painkillers or cream to try and cool my skin down. I just persevered. I would look at the leaflet, showing the guy on week 3, with a smile and I would think.."Wait till I get hold of you, you lyin barsteward!"
After the 4 weeks were up, I looked like an extra out of 'Burning Inferno'
Local schools asked me to come do a talk on the 'Dangers of Masturbation'!
The local Red Cross group asked if I would come along on a Monday evening so their volunteers could practise on a burn victim!
When the the traffic lights up the road blew a fuse, the council asked if I would stand in as a STOP sign!
Two weeks later though and the skin sloughed off and I was left with skin that hadn't been that soft since I was in nappies.
It didn't get rid of it all though. I still get a few spots back on my nose and head.
Would I use it again?
Yes, it is still better than having lumps cut out of you..
|
| Sutiro |
Posted - 05/07/2013 : 18:52:27
I'd like to do one more post to sum up my experience. It may provide some feedback for those considering the treatment. I completed a 21 day, two applications per day regime on my forehead in February. Fourteen days later a two square inch scab peeled off leaving a smooth pink patch of skin. This patch is still evident three months later. I then commenced another regime on a larger area on the top of my head with the efudix cream I had left. I had enough for two applications per day for ten days and then once per day for three days more, then let it heal. The skin reacted within two days with lots of neon lights appearing. The whole process was completed in three weeks and the result was excellent. Ten sunspots were completely removed, no blemishes and the skin left smooth. I'm of the opinion that for me the 21day, twice a day regime was overkill and it burnt the skin more than was necessary. I am an obvious fan of efudix and am pleased to be able to have control of the condition into the future. I hope this has been of help to someone and thank you to those who provided me with feedback when I needed it.
Cheers |
| JackRussell |
Posted - 04/10/2013 : 07:58:20
Danny -
I would be highly suspect if no reaction whatsoever was seen after one month. Either the product was defective or it wasn't being applied properly. It has to be applied twice a day to clean dry skin. For an area the size of the face you will use a tube in not much more than 2 weeks. You cannot apply anything to the face for at least 2 hours after applying it.
It is vertually impossible not to get a reaction after 30 days. Inevitably, over that amount of time, the Effudex would effect some normal cells. Effudex is carpet bombing and some good cells get called up in the campaigne. |
| andrewecd |
Posted - 04/09/2013 : 17:32:51
Danny, from what I understand that is good as you have no abnormal cells to react? |
